thyroglobulin


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thy·ro·glob·u·lin

 (thī′rō-glŏb′yə-lĭn)
n.
1. A thyroid protein that assists in the synthesis of the iodine-containing hormones thyroxine and triiodothyronine and is typically present in the colloid of thyroid gland follicles.
2. A substance extracted from the thyroid glands of hogs, formerly used as a thyroid hormone supplement to treat hypothyroidism.

thyroglobulin

(ˌθaɪrəʊˈɡlɒbjʊlɪn)
n
(Biology) a protein which is found in the thyroid gland and which contains iodine
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thyroglobulin - an iodine containing protein that is obtained from the thyroid gland and exhibits the general properties of the globulins
iodinated protein, iodoprotein - a protein that contains iodine
Translations

thy·ro·glob·u·lin

[MIM*188450]
n. tiroglobulina.
1. iodina que contiene glicoproteína secretada por la tiroides;
2. sustancia que se obtiene de tiroides porcinas y se administra como suplemento en el tratamiento de hipertiroidismo;
___ antibodyanticuerpo de ___.

thyroglobulin

n tiroglobulina
References in periodicals archive ?
1] Nonstandard abbreviations: ATD, autoimmune thyroid diseases; TPO, thyroid peroxidase; Tg, thyroglobulin.
Immunohistochemical studies were carried out on the cell block and core biopsy sections using antibodies TTF-1 (1:200; Leica), thyroglobulin (1:1000; Dako), ER (1:50; Dako), PR (premade; Leica), GATA3 (1:200; Cell Marque), GCDFP-15 (1:500; Leica), CD56 (Premade; Leica), synaptophysin (1:200; Dako), chromogranin (1:200; Cell Marque), pAx8 (1:100; Cell Marque), villin (1:100; Leica), CK 7 (1:400; Dako) and CK20 (1:200; Novocastra).
The IHC characterization of the thyroid cells was performed with antibodies against thyroglobulin (specific for thyroid follicular cells) and calcitonin (specific for thyroid C-cells [or parafollicular cells]) (RAMOS-VARA et al.
Apart from the aforementioned points, the discrepancy between the actual thyroglobulin (Tg) level and the posttreatment imaging findings has also been mentioned as a weighing factor for high recurrence risk in the ATA guidelines, based on its predictive value for both ablation success and prognosis.
A total body scan 8 weeks post laminectomy (when 24 hour urine iodine < 100 microgram/litre, and TSH was 38 mIU/ml after thyroid hormone withdrawal) was negative, the thyroglobulin level was 5 ng/ml and negative antithyroglobulin antibody (at that period of time, positron emission tomography (PET) scan was not an available option).
Diagnostic value of serum thyroglobulin measurements in the follow-up of differentiated thyroid carcinoma, a structured meta-analysis.
5) It exhibited organoid and trabecular pattern with hyalinized stroma, positive immunostaining for calcitonin and negative staining for thyroglobulin.
1) In order to establish iodine status in an individual with thyroid disease or suspected thyroid disease, I suggest using a 24 hour iodine urine test and a serum thyroglobulin test.
To the Editor: I read the recent article (1) on the relationship between thyroglobulin and recurrence of thyroid cancer with great interest.
When thyroid cancer metastasizes, lymph nodes in the neck may be affected, but these lymph-node tumors can be tiny and may not be detected by ultrasounds done before surgery to remove the diseased thyroid--or even during the procedure itself, hi an international academic study published in the December issue of the journal Surgery, UCLA researchers and colleagues demonstrated that routine removal of neck lymph nodes during initial thyroid surgery for papillary cancer may lead to lower disease recurrence rates and lower levels of thyroglobulin, a thyroid tumor marker that can be an indicator of disease when elevated.