thyroxine-binding globulin


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thy·rox·ine-bind·ing globulin

 (thī-rŏk′sēn′bīn′dĭng, -sĭn-)
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
Decreased Thyroxine-binding Globulin-Androgens, including JATENZO, may decrease concentrations of thyroxine-binding globulin, resulting in decreased total T4 serum concentrations and increased resin uptake of T3 and T4.
There are reasons that immunoassays could potentially be inaccurate during pregnancy, including the fact that pregnant women have higher concentrations of thyroxine-binding globulin and nonesterified fatty acids that could, in theory, alter the properties of immunoassays developed and validated with use of nonpregnant serum.
We measured immune reactivity of either target specific monoclonal or polyclonal antibodies for TSH receptor, 5'deiodinase, thyroid peroxidase, thyroglobulin, thyroxine-binding globulin, thyroxine, and triiodothyronine against 204 purified dietary proteins that are commonly consumed in raw or cooked forms.
Changes in serum TSH, T4, T3, thyroxine-binding globulin, reverse T3 and free T4 and T3 concentrations.
Thyroxine-binding globulin concentrations increase primarily because of decreased clearance resulting from increasing estrogen concentrations and an increase in urinary iodine excretion, particularly in the first trimester.
Approximately 99.7% of T3 is bound to protein (TBG; thyroxine-binding globulin), with the remaining circulating as free T3.
Once inside the thyroid follicular cells, [T.sub.3] and [T.sub.4] are cleaved from thyroglobulin, Free [T.sub.3] and [T.sub.4] are then released into the bloodstream, where they are bound to serum proteins for transport, the major one being thyroxine-binding globulin (TBG), which has high affinity but low capacity for [T.sub.3] and [T.sub.4].
The thyroid hormones are >99% bound to thyroxine-binding globulin, thyroxine-binding prealbumin and albumin in plasma.
Thyroxine-binding globulin in patients with chronic hepatitis B virus infection: different implications in hepatitis and hepatocellular carcinoma.
Neonatal screening for congenital hypothyroidism based on thyroxine, thyrotropin, and thyroxine-binding globulin measurement: potentials and pitfalls.
* Almost all (approximately 99%) circulating [T.sub.3] and [T.sub.4] is bound to a protein called thyroxine-binding globulin (TBG).