References in periodicals archive
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In an in vitro experiment,[2] ticagrelor was shown to increase the concentration of extracellular adenosine by inhibiting its uptake by red blood cells.
Anglo-Swedish pharmaceutical firm AstraZeneca (LON: AZN) has issued a voluntary US recall for one lot of professional (physician) sample bottles of BRILINTA (ticagrelor) that contain eight 90mg tablets.
In a Medwatch alert in July 2015, the FDA noted that prescribing and dispensing errors had occurred because of the similarity in names of Brintellix and the blood thinner Brilinta (ticagrelor).
15 September 2010 - Anglo-Swedish pharma major AstraZeneca (LON: AZN) (STO: AZN) said today the US Food and Drug Administration (FDA) postponed its decision on experimental blood thinner Brilinta (ticagrelor) by three months to 16 December 2010.
-- The Food and Drug Administration's Cardiovascular and Renal Drugs Advisory Committee voted 7-1 to recommend approval of the platelet inhibitor ticagrelor to treat non-ST elevation myocardial infarction and ST-elevation myocardial infarction in patients intended to receive primary coronary intervention or who would be managed medically.
PhaseBio Pharmaceuticals announced that results from the Phase 1 clinical trial of PB2452, a novel reversal agent for the antiplatelet drug ticagrelor, demonstrated that PB2452 provided immediate and sustained reversal of ticagrelor antiplatelet effects without report of drug-related serious adverse events.
Background: There was still conflict on the antithrombotic advantage of ticagrelor versus clopidogrel among East Asian population with acute coronary syndrome (ACS).
CHICAGO--The benefit from dual-antiplatelet therapy in high-risk patients following a myocardial infarction was especially apparent in post-MI patients with diabetes in a prespecified secondary analysis from a multicenter trial of ticagrelor with more than 21,000 patients.
AstraZeneca, a British-Swedish multinational pharmaceutical and biologics company, has received marketing authorisation from the European Commission for its Brilique (ticagrelor), it was reported yesterday.
27 July 2010 - The Office of Clinical Pharmacology (OCP) under the US Food and Drug Administration (FDA) has recommended approval of experimental blood thinner Brilinta (ticagrelor) by Anglo-Swedish pharma major AstraZeneca plc (LON: AZN) (STO: AZN) but the market is divided on the news.
ORLANDO -- The investigational reversible oral antiplatelet drug ticagrelor proved superior to clopidogrel in all-cause mortality and other key end points in a major randomized trial involving 8,430 patients with ST-elevation MI.
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