kallikrein

(redirected from tissue kallikrein)
Also found in: Medical.
Related to tissue kallikrein: kallikrein serine protease 1

kallikrein

(ˌkælɪˈkriːɪn; kəˈlɪkriːɪn)
n
(Biochemistry) a type of protease that liberates kinins from kininogens
Translations

kal·li·kre·in

n. calicreína, enzima potente de acción vasodilatadora.
References in periodicals archive ?
The paper, entitled Safety, tolerability, and pharmacokinetic profile of recombinant human tissue kallikrein, DM199, after intravenous and subcutaneous administration in healthy volunteers, established the pharmacokinetic profile of DM199 when administered intravenously or subcutaneously in 36 healthy volunteers.
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients.
Kinins derived from kininogen produced by tissue kallikrein (TK) exert a broad spectrum of cellular functions via activation of the bradykinin B1 or B2 receptor (B1R or B2R, resp.
Transcriptional upregulation of human tissue kallikrein 6 in ovarian cancer: clinical and mechanistic aspects.
We previously reported that inhalation challenge with a variety of noxious agents results in increased tissue kallikrein activity and subsequent kinin generation in the airways.
carried out a study to elucidate the differential roles of bradykinin B1 receptor and B2 receptor underlying the effect of tissue kallikrein on the stroke outcome in diabetic rats.
Association of the tissue kallikrein gene promoter with ESRD and hypertension.
The human tissue kallikrein (KLK) [3] family consists of 15 genes located in tandem on chromosome 19q13.
Further evidence has shown that human tissue kallikrein 7 (KLK7) [6] mRNA is significantly up-regulated in ovarian tumors (20, 21).
Expanded human tissue kallikrein family: a novel panel of cancer biomarkers.