tissue plasminogen activator

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Related to tissue plasminogen activator: streptokinase

tissue plasminogen activator

n. Abbr. tPA or TPA
1. A clot-dissolving enzyme that is produced naturally by cells in the walls of blood vessels and catalyzes the conversion of plasminogen to plasmin.
2. A preparation of this enzyme that is produced by genetic engineering and is used as a drug to dissolve blood clots in the immediate treatment of certain cases of stroke and heart attack.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


or tPA,

tissue plasminogen activator: an anticlotting enzyme of the blood, produced in quantity by genetic engineering for use in dissolving blood clots.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tissue plasminogen activator - a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clottissue plasminogen activator - a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clot; used in treating acute myocardial infarction
clot buster, thrombolytic, thrombolytic agent - a kind of pharmaceutical that can break up clots blocking the flow of blood to the heart muscle
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.

tissue plasminogen activator (tPA)

n activador m tisular del plasminógeno, activador del plasminógeno tisular
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Although the abbreviations "tPA," "TPA," or rt-PA" are often used when referring to alteplase, they are also used when referencing the larger class of recombinant tissue plasminogen activator medications.
Injection of tissue plasminogen activator into a branch retinal vein in eyes with central retinal vein occlusion.
Though limited by a smaller number of postimplementation cases and lack of 3-month poststroke functional outcome data, the findings suggest that 24/7 in-hospital availability of a neurologist improves door to intravenous tissue plasminogen activator treatment times and in-hospital stroke mortality, Dr.
Vehar, "Interaction of one-chain and two-chain tissue plasminogen activator with intact and plasmin-degraded fibrin," Biochemistry, vol.
Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke.
'Alteplase, or tissue plasminogen activator, is ideally given in the first three hours upon onset of acute stroke,' Tayag said at a press briefing, stressing that only patients who have an ischemic type of stroke, or those with blocked blood vessels in the brain, will benefit from the medicine since alteplase breaks down unwanted blood clots.
Known as tissue plasminogen activator (tPA), it is already available in neighbouring countries, but concerns over its safety and logistics have delayed its use in Bahrain.
In the case of a mild stroke, doctors are often reluctant to administer tissue plasminogen activator (tPA), a drug that helps dissolve blood clots.
To receive the Target: Stroke Honor Roll-Elite award, South Nassau fulfilled quality measures developed to reduce the time between the patient's arrival at the hospital and treatment with the clot-buster tissue plasminogen activator, or tPA, the only drug approved by the U.S.