Large-bowel obstruction should be considered if the colonic diameter is greater than 6 cm and in the presence of air-fluid levels, although these findings are not specific for obstruction and can be seen with paralytic ileus and toxic megacolon
. Complications of LBO including pneumatosis intestinalis, pneumoperitoneum, and portal venous gas.
(1) Its manifestations range from being relatively benign (nausea, vomiting, constipation) to potentially severe (fecal impaction) or even life-threatening (bowel obstruction, ileus, toxic megacolon
One week later, the appearance of toxic megacolon
required venting ileostomy to be performed.
It is commonly associated with antibiotic use and the life-threatening complications include pseudomembranous colitis, toxic megacolon
, perforation of the colon and death.
Unusual but serious complications such as fulminant necrotizing colitis, toxic megacolon
, and fistulizing perianal ulcerations can occur, especially when diagnosis and treatment is not timely [1, 26, 27].
difficile) is a spore-forming pathogen that typically causes symptoms in individuals with altered gut microbial flora, releasing toxins that can result in a range of disease manifestations from asymptomatic colonization to diarrhea, pseudomembranous colitis, toxic megacolon
, intestinal perforation, or, in the most severe cases, death.
In an immunocompromised patient, CMV infection of colon can present in a variety of ways: ulcers, proctocolitis, pseudotumors, pseudomembranes, appendicitis, perforation, pneumatosis intestinalis, or toxic megacolon
At 21 years old, she underwent total abdominal colectomy with end ileostomy for toxic megacolon
during a twin pregnancy when she stopped her antimetabolite therapy.
Rates of toxic megacolon
were equal (7% each group); ileus was more frequent in the tigecycline group (11% vs.
Surgery is generally reserved for patients with intractability, colorectal cancer, toxic megacolon
, massive bleeding or perforation.
His abdomen was distended and he had toxic megacolon
. Dr Kumar conducted a total colectomy, removing the entire length of the large intestine and excised several parts of his small intestines, cleaned up the decay and put an external drain.