Summary: Quantitative structure-activity relationships were constructed for 107 inhibitors of HIV-1 reverse transcriptase
that are derivatives of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
the subject of the order in the scope of lot 1 is the supply at the cost and risk of the medical device contractor for the genotypic determination of hiv resistance to anti-retroviral drugs - reverse transcriptase
inhibitors and protease inhibitors, to laboratories performing research for health policy implementers treating hiv / aids patients, working on the basis of hospitals / medical facilities who have concluded agreements with the national center for aids for the implementation of the health policy of the minister of health, entitled "antiretroviral treatment of people living with hiv in poland for 2017-2021".
The alteration occurs in the telomerase reverse transcriptase
gene, which helps to produce the enzyme telomerase.
This family of viruses uses molecular machinery called reverse transcriptase
M2 PHARMA-November 20, 2014-New England Biolabs unveils next generation thermostable reverse transcriptase
for nucleic acid detection
Rilpivirine is a non-nucleoside reverse transcriptase
inhibitor and is presently being marketed as Edurant, while dolutegravir is an integrase inhibitor marketed as Tivicay.
Researchers from the Republic of Korea isolated a population of stem cells derived from dental tissues of third molars and found that human dental papilla stem cells--DpaSCs that develop into dentin and dental pulp--have biological features similar to bone marrow-derived mesenchymal stem cells (MSCs) in terms of telomere length, telomerase activity and reverse transcriptase
AZT works by inhibiting an enzyme, reverse transcriptase
, which HIV needs to produce DNA from RNA, and thus replicate itself.
Thermo Fisher Scientific, the world leader in serving science, have announced that the DuPont Qualicon BAX[R] System Reverse Transcriptase
8-hour Listeria Assay is now available alongside the Oxoid range in Europe, Canada, Australia and New Zealand.
A single dose of tenofovir and emtricitabine at delivery reduced resistance to nonnucleoside reverse transcriptase
inhibitors at 6 weeks after delivery by half.
The group conducted a study, published recently in the New England Journal of Medicine, that investigated the association of cumulative exposure to protease inhibitors and non-nucleoside reverse transcriptase
inhibitors with the risk of myocardial infarction.
Identify the primary functions of each of the following viral proteins: gp120, gp41, reverse transcriptase
, integrase, protease.