transgene


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trans·gene

 (trăns′jēn′, trănz′-)
n.
A gene used in transgenesis.

transgene

(ˈtrænzˌdʒiːn)
n
(Genetics) genetics a gene that is transferred from an organism of one species to an organism of another species by genetic engineering
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.transgene - an exogenous gene introduced into the genome of another organism
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
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References in periodicals archive ?
- French biotechnology company Transgene (PAR: TNG) this week provided an update on the interim futility analysis of the PHOCUS study of Pexa-Vec in liver cancer, the company said.
The ability to safely re-dose AAV should help achieve therapeutic benefit in patients who are under-dosed; it should also help restore transgene expression in patients, particularly growing pediatric patients, who may lose expression over time.
France-based Transgene has announced that the independent Data Monitoring Committee (IDMC) for the PHOCUS study of Pexa-Vec in Liver Cancer has completed a planned interim futility analysis, it was reported yesterday.
Biotech company Transgene (Paris:TNG) said on Monday that it has dosed the last patient under the Phase 2 trial evaluating TG4010 in combination with Opdivo (nivolumab) and chemotherapy as a first-line treatment for advanced non-squamous non-small cell lung cancer (NSCLC).
TOKYO, Oct 30, 2018 - (JCN Newswire) - NEC Corporation (TSE: 6701) and Transgene today announced the signing of a Memorandum of Understanding (MOU) for a strategic collaboration aimed at the treatment of solid cancers.
21 August 2018 - French virus-based immunotherapies developer Transgene (PAR: TNG) has closed transactions signed with Chinese drugmaker Tasly Biopharmaceuticals.
Here we isolated a pure population of osteoblasts from intramembranous bone of neonatal mice carrying both Osx1-GFP::Cre and Oct4-EGFP transgenes. Daily monitoring of the reprogramming process revealed initial silencing of Osx1-GFP::Cre transgene expression followed by late activation of Oct4-EGFP expression when iPS cells were formed with comparable reprogramming efficiency as skin fibroblast-derived iPS cells.
This plasmid, carrying this intended "transgene," would be introduced into a tissue culture "packaging cell line" that has been engineered to also express the required AAV viral capsid proteins and the required "helper virus" genes.
Transgene and Randox have entered into a collaboration to combine their technologies and develop multifunctional oncolytic immunotherapies.
Servier and Transgene have signed a research agreement on the application of viral vectorization technology for the production of allogenic CAR-T cell therapies.
Recently developed transgene delivery techniques and genome editing tools will advance biotechnology research areas much more rapidly.