After two washings with phosphate buffered solution (PBS), expression of transmembrane
CXCL16 in cells was analyzed with a Becton Dickinson FACScan using a software FACS express 3 (De Novo Software, Los Angeles, CA).
We have adopted this criterion for both representations applied in transmembrane
segments classification study.
Based on previous research, the researchers hypothesized that 17[beta]-estradiol and the EDCs would bind to nonclassical estrogen receptors on the membrane of glucagon-producing [alpha]-cells and activate a sequence of secondary messengers within the cell, leading to control of the transmembrane
calcium channel and related calcium oscillations.
(3) One of these kinases is the epidermal growth factor (EGF) receptor (EGFR) gene, which encodes a transmembrane
receptor for EGF-family ligands.
Additional characterization of these mutants was done in three replication by ONPG (o- nitro-phenyl-galactoside) spectrophotometric assays providing quantitative measurements that disruption of the hydrophobic transmembrane
helices disrupts function of the protein.
Exon 3 encoded a hydrophilic domain containing multiple stop codons that would result in truncation of MOG prior to translation of its transmembrane
It now appears that individuals who just carry one cystic fibrosis mutation have a subtle dysfunction in the cystic fibrosis transmembrane
regulator (CFTR) protein.
Because of a genetic defect, people with cystic fibrosis lack functional copies of a protein called the cystic fibrosis transmembrane
conductance regulator (CFTR), which works like a channel to control the flow of chloride ions in and out of cells.
Food and Drug Administration approved SYMDEKO for use in children with cystic fibrosis ages 6 through 11 years who have two copies of the F508del-CFTR mutation or who have at least one mutation in the cystic fibrosis transmembrane
conductance regulator gene that is responsive to SYMDEKO.
The committee has recommended the product to treat cystic fibrosis patients in the age category who have at least one of the following nine mutations in their cystic fibrosis transmembrane
conductance regulator (CFTR) gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or S549R.
Pierre et Marie Curie, Paris; AP-HP Hopital Charles Foix, Centre de Recherche et Developpement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane
proteins), and gap junction-related diseases due to mutations in connexin genes.