Immuron announced plans to pursue clinical development of IMM-124E, its bovine polyclonal antibody drug candidate, through a formal FDA registration pathway as a drug to prevent travelers' diarrhea
, or TD.
According to the agency, the efficacy of Aemcolo was demonstrated in a randomised, placebo-controlled clinical trial in 264 adults with travelers' diarrhea
in Guatemala and Mexico.
The go-to "pink stuff" can be taken for a range of common stomach ailments, including diarrhea, travelers' diarrhea
, nausea, heartburn, indigestion or an upset stomach due to overindulgence in food and drink.
CHICAGO -- An investigational antibiotic was just as effective as ciprofloxacin at curing travelers' diarrhea
but was associated with a significantly lower rate of colonization with extended spectrum beta-lactam-resistant Escherichia coli, a phase III trial has determined.
: Prevention, treatment, and post-trip evaluation.
Lesaffre Human Care offers both food grade and baby food grade versions of LifeinU LRGG, which can, according to the company, protect the gut from antibiotic associated diarrhea and prevent gastrointestinal infections such as travelers' diarrhea
, as well as boost the body's natural defenses to reduce occurrences of the common cold.
Several factors have been identified to increase the risk for ESBL-E colonization: travel destination (2-7), travelers' diarrhea
(TD) (2,6,7), use of AMDs (5-7), and age (2,6).
Travelers should be encouraged to 1) observe food, water, and hand-hygiene precautions while traveling; 2) use over-the-counter medications like bismuth subsalicylate (e.g., Pepto-Bismol) or loperamide (e.g., Immodium) if they wish to treat mild or moderate travelers' diarrhea
; 3) reserve antimicrobial medications for severe cases of travelers' diarrhea
; 4) seek health care if they are experiencing diarrhea upon return to the United States or develop diarrhea shortly thereafter; and 5) remain vigilant regarding hygiene practices while ill.
Incidence and impact of travelers' diarrhea
among foreign backpackers in Southeast Asia: a result from Khao San road, Bangkok.
The practice recommendation should have read: "Advise travelers to initiate self-treatment for travelers' diarrhea
with a fluoroquinolone (or azithromycin if in South or Southeast Asia) at the onset of diarrhea if it is bloody or accompanied by fever:'
NoVs were identified in 10% of cases of travelers' diarrhea
, and overall were the second most common pathogen following diarrheagenic Escherichia coli.
and toxigenic Escherichia coli.