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A surgical instrument with a cylindrical saw usually used for removing a disk of bone, especially from the skull, or for removing corneal tissue.
tr.v. tre·phined, tre·phin·ing, tre·phines
To operate on with a trephine.

[French tréphine, from obsolete English trefine, from Latin trēs fīnēs, three ends : trēs, three; see trei- in Indo-European roots + fīnēs, pl. of fīnis, end.]

treph′i·na′tion (trĕf′ə-nā′shən) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.trephination - an operation that removes a circular section of bone from the skulltrephination - an operation that removes a circular section of bone from the skull
surgical operation, surgical procedure, surgical process, surgery, operation - a medical procedure involving an incision with instruments; performed to repair damage or arrest disease in a living body; "they will schedule the operation as soon as an operating room is available"; "he died while undergoing surgery"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n. trefinación, acto de cortar un tejido o un hueso con un corte circular o de disco, operación gen. efectuada en el cráneo.
English-Spanish Medical Dictionary © Farlex 2012
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References in periodicals archive ?
Burr-hole craniostomy (also known as trepanning, trepanation, trephination, trephining) is a time-tested intervention in which a hole is drilled or scraped into the human skull, exposing the dura-mater to release pressured blood build-up from an injury or manage issues pertinent to intracranial diseases.9 Various international researchers have compared the single-hole and double-hole drilling, but unfortunately reported follow-up periods are short-lived, often limited to acute hospitalization.3 Although neurosurgical clinics in Pakistan frequently manage clients of CSDH, nevertheless, formal studies are skimpy and no such study has yet been conducted at subject hospital.
A sinus trephination procedure was performed through the maxillary bone for sinoscopy and sample collection and topical treatment.
Effect of trephination on postoperative pain and swelling in symptomatic necrotic teeth.
Trephination was practiced by Incas and their tradition holds the "Shaman" performing the procedure, chewed cocoa leaves and spitted into the wound, producing the local anaesthetic effect.
First, he presented with a medial frontal mucocele and Kuhn type 4 cell, which required additional sinus trephination through an eyebrow incision.
All DM grafts underwent superficial trephination using an 8.0 mm punch, which is one of the most preferred diameters in DMEK surgery.
showed that the introduction of autologous chondrocytes alongside conventional trephination and suture techniques improved the healing avascular zone tears in an ovine knee injury model [32].
If surgery is contraindicated or a different treatment is desired, treatment with percutaneous trephination or drill resection with or without subsequent injection of ethanol has been reported.
In patients with bullous keratopathy or Fuchs dystrophy in which cell migration is a prominent phenomenon, a large trephination diameter can help reduce chronic endothelial cell loss after PKP, resulting in a clear graft after cell migration from the donor to the host.
Trephination was also employed for seizures throughout the nineteenth century (R.
Shamans bored the skull of live patients to make burr holes, a process called trephination to allow these spirits to escape.[2] In the 17th century, Thomas Willis proposed that migraine was caused due to vasodilatation of cerebral vessels, closely afterward Eulenberg tried to explain the disorder by strategically placing vasoconstriction and vasodilatation mechanisms at different stages of the phenomenon.[3] Now, we believe the neurovascular theory of migraine where neurogenic inflammation activates a vascular cascade and the symptoms produced thereof are a consequence of the two pathways.[4] However, the pathogenesis of the disorder has not yet been elucidated.