punch biopsy

(redirected from trephine biopsy)
Also found in: Medical.
Related to trephine biopsy: Bone marrow aspiration
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punch biopsy
dashed rules outline the portion of skin to be removed for biopsy

punch biopsy

n.
1. The removal of a small cylindrical specimen of tissue for pathologic study by pressing a circular instrument into the skin or mucous membrane surrounding a lesion.
2. A specimen so removed.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
FDG PET/CT bone/bone marrow findings in Hodgkin's lymphoma may circumvent the use of bone marrow trephine biopsy at diagnosis staging Eur J Nucl Med Mol Imaging 201037:1095-105.
He had been to various hospitals and investigations including blood complete picture, blood culture and sensitivity, mantoux test and bone marrow aspiration and trephine biopsy were carried out.
Furthermore her bone marrow trephine biopsy was done which showed clusters of mature megakaryocytes with multi-lobulated staghorn nucleoli, suggestive of Essential thrombocytosis.
Interactions between the bone and the BM microenvironment and tumour cells plays a central role in the homing of tumor cells to marrow with consequent bone metastasis.16-18 Bone marrow infiltration was detected in 42 (50.6%) children in our study with 20/42 cases (47.6%) showing infiltration both on aspirate and trephine biopsy, isolated marrow aspirates were positive in 08 cases while isolated marrow core biopsies were positive in 14 cases.
Ideally in all the cases of peripheral pancytopenia, especially if hypoplastic or aplastic anaemia is suspected, both aspiration and trephine biopsy should be done simultaneously because bone marrow biopsy gives a more reliable index of cellularity and reveals bone marrow infiltration, fibrosis and granulomas.
Histology and bone marrow trephine biopsy results showed French American British (FAB) classification [3] as AMML-M4 and as World Health Organization (WHO) classification 2008 [4].
Bone marrow trephine biopsy showed slightly hypocellular marrow for the patient's age, with trilineage hematopoiesis.
Bone marrow aspiration and trephine biopsy were sought for evaluation of pancytopenia in a 22-year-old adolescent male who presented with severe weakness, fatiga-bility, and increasing breathlessness for last 6 months.
Trephine biopsy of the bone marrow specimen stained with hematoxylin and eosin (A and B); Alcian blue (C and D).
Bone marrow trephine biopsy revealed trilineage haematopoiesis with increased plasma cells.
* bone marrow trephine biopsy: multifactorial cause of anaemia, no obvious infiltrates