Caused by Treponeme
bacteria, DD has been affecting the majority of UK dairy herds since 1987.
pallidum strains Nichols and SS14: correction of sequencing errors resulted in increased separation of syphilis treponeme
subclusters," PLoS ONE, vol.
This attachment, which is thought to involve adhesin molecules on the treponeme
and complementary ligands and extracellular matrix components of the host cell, facilitates the pathogen movement into the tissue (3,12).
The spirochetes include a thin treponeme
morphologically indistinguishable from Treponema pallidum, a Borrelia-like medium-sized 5:4:5 or 4:8:4 spirochete attached at the posterior periphery of the cell's wood ingestive zone, and Canaleparolina sp., a larger and longer spirochete (26-28[micro]m length X 0.4-0.7[micro]m width) known only from two remotely separated localities (Darwin, Australia, and St.
La maladie du sommeil avait toujours existe, disait-on et << si elle etait aussi meurtriere, tout le pays serait depuis longtemps depeuple >> ; << Jamot confond le trypanosome avec le treponeme
de la syphilis et du pian >>, affirmait le directeur du service de sante du Cameroun.
The accuracy of genetic signatures for different treponeme
strains has yet to be established, they say.
Contributors offer their research in the molecular genetics of spirochetes (including the isolation and characterization of isogenic mutants, motility gene regulation and chemotaxis and development of treponeme
genetic systems), genetics and diversity (including comparative genetic studies and those of genotypic variation), gene expression, and interactions of spirochetes and hosts, including Lyme disease and relapsing conditions.
Although the treponemal serologic status of the pet owners in this study is unavailable, the fact that seropositive pet NHPs from a region neighboring an area with a high number of human yaws cases suggests that the NHP cases resulted from treponeme
transmission from humans to pets.
palladum and new insights into Treponeme
diversity, genomics, and cellular and molecular biology.
Since it takes several weeks for the mother and baby to mount antibody response to the treponeme
, they might have tested negative at the time of delivery.[11,12] Another explanation is that, in primary syphilis, nonreactivity to the nontreponemal test is reported to occur in approximately 25% of cases.[11,12] A negative serological test may also be the result of a prozone phenomenon, which occurs when an excess of antibodies in a given specimen prevents flocculation[11-13]; when the same specimen is diluted, it will exhibit titers of 1:16 or more.
* Treponema sp., a Gram-negative bacterium; compelling evidence is showing that treponemes
are involved in the etiology of several chronic diseases, including periodontitis and other forms of periodontal disease.
pallidum subspecies from nonpathogenic treponemes
, other spirochetes, and 59 species of bacteria and viruses including those causing genital ulcers in humans (14).