The effective nonsteroidal aromatase inhibitors, Letrozole, Vorozole, and Anastrozole, having triazole
moieties, are useful for preventing breast cancer .
Fosravuconazole, the active ingredient of NAILIN Capsules 100mg, is a new triazole
class oral antifungal component discovered by Eisai.
Tortop described Revysol as "an innovative and highly effective fungicide active ingredient from the triazole
fumigatus to triazole
and the underlying cyp51A mutations in triazole
Synthesis of the triazole
compounds accomplished in six steps.
antifungal agents play an important role in the treatment of a wide range of fungal infections and can save lives when used in treatment of systemic invasive fungal infections in severely ill patients.
Pharmacodynamics of a new triazole
, posaconazole, in a murine model of disseminated candidiasis.
The approved indications for this triazole
antifungal agent are prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients, as well as treatment of oropharyngeal candidiasis.
antifungal drugs, including itraconazole, are most commonly used for treatment; however, itraconazole treatment failures from drug resistance are becoming more common, requiring newer treatment options.
They found that the best-performing materials were all modified with molecules containing a triazole
group -- a ring containing two carbon atoms and three nitrogen atoms.
Well-known drugs with such effects include several macrolide antibacterials and triazole
antifungals and preemptive tacrolimus dose-reduction has been proposed when drugs are to be administered concomitantly [3,12].
The guidelines note that most of the evidence for managing CPA are based on cohort studies and case reports rather than randomized clinical trials, and that there have been no head-to-head trials comparing oral triazole