trichothecene


Also found in: Medical, Acronyms, Wikipedia.

trichothecene

(ˌtrɪkəʊˈθiːsiːn)
n
(Biochemistry) a member of a large family of chemically related mycotoxins
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

tri•cho•the•cene

(ˌtraɪ kəˈθi sɪn)

n.
any of a group of toxins derived from various imperfect fungi, as of the genera Fusarium and Trichothecium.
[1970–75; < New Latin Trichothec(ium) (tricho- tricho- + thecium < Greek thēkíon, diminutive of thḗka case) + -ene]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
Hermosa et al., "Identification of loci and functional characterization of trichothecene biosynthesis genes in filamentous fungi of the genus Trichoderma" Applied and Environmental Microbiology, vol.
Production of trichothecene mycotoxins by Fusarium graminearum and Fusarium culmorum on barley and wheat.
The trichothecene mycotoxins are a group of toxic secondary metabolites characterized by the tetracyclic 12, 13-epoxy trichothecenes, since they all have an olefinic bond at C9, 10 and the epoxy ring at C12,13 (Bamburg et al.
Samples contained the potent protein synthesis inhibitor Satratoxin H, a member of the Trichothecene mycotoxin group that causes immunosuppression.
The toxin, called T-2 toxin, is a trichothecene that is a natural contaminant of food and livestock feed.
Wan et al [27] revealed that due to trichothecene toxicity, IGFBP4, an insulin-like growth factor (IGF)-binding protein, was suppressed in the rat pituitary adenoma gretchen hagen 3 (GH3) cells, demonstrating that the T-2 toxin gave rise to a growth hormone-IGFBP4 deficiency in the cells.
Stachybotrys chartarum, trichothecene mycotoxins, and damp building-related illness: new insights into a public health enigma.
Similar ribosomal RNA injuries have been observed during nonprotein ribosome-inactivating stress triggered by physical and chemical insults such as ultraviolet (UV) irradiation, trichothecene mycotoxins (mostly cereal contaminants produced by molds such Fusarium species), palytoxin (an intense vasoconstrictor produced by marine species including dinoflagellate Ostreopsis ovata), and anisomycin (an antibiotic produced by Strep tomyces griseolus), which also interfere with peptidyltrans ferase activity by directly or indirectly modifying 28s rRNA [11, 12].
Yatawara (1986), "Airborne Outbreak of Trichothecene Toxicosis," Atmospheric Environment, 20:549-552.
They have successfully disarmed the fungus' ability to produce its toxin, trichothecene, by identifying the gene that is responsible for the production of an enzyme, trichodiene synthase.