So far, the assay has been mostly evaluated with strong positive control sensitizers (2,4-dinitrochlorobenzene, trinitrobenzene
sulfonic acid), showing a response of no more than 4% of T cells.
Abbreviations FD: Functional dyspepsia 5-HT: 5-Hydroxytryptamine m-CPBG: m-Chlorophenylbiguanide CRF: Corticotropin-releasing factor TNBS: Trinitrobenzene
sulfonic acid HPA: Hypothalamus-pituitary-adrenal ACTH: Adrenocorticotrophic hormone CMUS: Chronic mild unpredictable stimulation HCI: Hydrochloric acid TGR5: Bile acid receptor 1 nNOS: Neuronal nitric oxide synthase FSL: Flinders Sensitive Line WKY: Wistar Kyoto BB-DP: BioBreeding diabetes-prone.
May have nitroaromatic structures [as in the case of musk xylene (1-ferf-butyl-3,5-dimethyl-2,4,6- trinitrobenzene
) or musk ketone (4-ferf-butyl-2,6-dimethyl-3,5- dinitroacetophenone)] or polycyclic structures [as in the case of 7-acetyl-1,1,3,4,4,6-hexamethyl- 1,2,3,4-tetrahydronaphthalene (AHTN; trade name, tonalide), 1,3,4,6,7,8- hexahydro4,6,6,7,8,8- hexamethylcyclopenta-(g)-2- benzopyran(HHCB; trade name, galaxolide), 4-acetyl-6-ferf-butyl1, 1-dimethylindan (ADBI; trade name, celestolide), dihydropentamethylindanone (DPMI; trade name, cashmeran), or 5-acetyl -1,1,2,3,3,6-examethylindan (AHMI, tradename phantolide)].
Dietary intervention with narrow-leaved cattail rhizome flour (Typha angustifolia L.) prevents intestinal inflammation in the trinitrobenzene
sulphonic acid model of rat colitis.
The protective effect of ABA has been demonstrated against trinitrobenzene
sulphonic acid- (TNBS-) induced colitis in Swiss male mice .
 studied the transformation of trinitrobenzene
by a Pseudomonas consortium that utilized trinitrobenzene
as the sole source of nitrogen, but not sole source of carbon.
METHODS: Experimental colitis was induced with 1 mL trinitrobenzene
sulfonic acid (TNBS) in 40% ethanol by intracolonic administration with 8-cm-long cannula under ether anesthesia to rats in colitis group and colitis + black cumin oil group.
(73) IL-13 has also been shown to be important in a surprising variety of extrapulmonary fibrosis models, including non-immune-based systems such as steatohepatitis and trinitrobenzene
sulfonic acid-induced colitis.
The aims of this study were to investigate, if the inflammation markers formed in trinitrobenzene
sulphonic acid (TNBS)-induced colitis affect the gastric tissue and to determine the possible protective effects of orally administered NS seed oil on the gastric tissue.
Zona-free blastocysts were placed at 4[degrees]C for 30 min in 15 mM trinitrobenzene
sulfonic acid (TNBS, Sigma) and then exposed to goat anti-dinitrophenol-BSA (ICN Biomedicals Inc., Irvine, CA) for 20 min at 39[degrees]C.
The cocatalyst has a double bond, electron-depleted by an electroattractive group including o-chloranyl (3,4,5,6-tetrachloro-1,2-benzoquinone), p-chloranyl (2,3,5,6-tetrachloro-1,4-benzoquinone), nitrobenzene, trinitrobenzene
, or tetracyanoethylene.
To test whether the relative amounts of essential fatty acids in the diet affects colitis-related damage, Natalia Nieto and her colleagues at the University of Granada in Spain induced ulcerative colitis in a group of rats by administering a substance known as trinitrobenzene
sulfonic acid through a tube into the animals' colons.