trisomy

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Related to trisomies: Trisomy 18

tri·so·my

 (trī-sō′mē, trī′sō′-)
n. pl. tri·so·mies
The condition of having three copies of a given chromosome in each somatic cell rather than the normal number of two.

[tri- + -som(e) + -y.]

tri′some′ n.
tri·so′mic adj.

trisomy

(ˈtraɪsəʊmɪ)
n
(Medicine) the condition of having one chromosome of the set represented three times in an otherwise diploid organism, cell, etc. Trisomy of chromosome 21 results in Down's syndrome
[C20: from tri- + (chromo)som(e) + -y3]

tri•so•my

(ˈtraɪ soʊ mi)

n.
a genetic deviation characterized by the presence of three chromosomes where there are usually a pair.
[1925–30; tri- + -some3 + -y3]
tri•so′mic, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a celltrisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
Down syndrome, Down's syndrome, mongolianism, mongolism, trisomy 21 - a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation
chromosomal aberration, chromosomal anomaly, chromosonal disorder, chrosomal abnormality - any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities
Translations

tri·so·my

n. trisomía, trastorno genético por el cual una persona posee tres cromosomas homólogos por célula en lugar de dos (diploide), lo cual causa deformaciones fetales serias.

trisomy

n trisomía; — 21 trisomía 21
References in periodicals archive ?
Several NGS platforms have proved the feasibility of the detection of fetal trisomies (2-5); however, these platforms come with relatively high costs and a sequencing time of 2-3 days.
When complete, GenSite will incorporate AproProbe and AproProbe Plus with a more fully developed enrichment mechanism offering women a meaningful, non-invasive alternative to amniocentesis for the screening of common trisomies," Dr.
M2 PHARMA-February 27, 2014-Illumina's verifi prenatal test lowers false positive rate of foetal trisomies 21 and 18 detection
2) By analyzing cfDNA from maternal plasma, it is now possible to screen for trisomies with high sensitivity and specificity.
Aneuploidy is the most frequent genetic disorder observed in live births and miscarriages; trisomies are the most prevalent, accounting for approximately 53% of all chromosome abnormalities.
These days, a five-cocktail probe can test blastocysts for autosomal trisomies such as Down syndrome; autosomal monosomies; X and Y numerical disorders such as Turner's syndrome and Klinefelter's syndrome; and translocations using fluorescent in situ hybridization (FISH).
As a result, the test will be able to provide additional data for the presence of subchromosomal microdeletions and autosomal trisomies for chromosomes 16 and 22, along with previously unveiled additional results for sex chromosome aneuploidies including an abnormal number of the X or Y chromosomes.
Although MLPA/rtPCR assay combines the accuracy of MLPA with the simplicity of rtPCR and can detect trisomies 13, 18, and 21 accurately, the assay requires 20 h to perform.
The new blood test can detect trisomies 13, 18, and 21 and gives pregnant women an alternative to more invasive diagnostic testing.
In women 36 or older, the study found no evidence of an elevated rate of trisomies among patients who had had recurrent miscarriages, compared with those who had had just one miscarriage, although the risk of trisomy associated with certain chromosomes increases with maternal age.
In 2008, however, there appeared a brace of reports that applied the emerging next-generation sequencing (NGS) technologies to the analysis of trisomies with DNA extracted from maternal plasma (8, 9).
Aria will use the financing for product development and commercialisation of its proprietary prenatal test to detect common fetal trisomies such as Trisomy 21, which is associated with Down syndrome.