trisomy


Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia.

tri·so·my

 (trī-sō′mē, trī′sō′-)
n. pl. tri·so·mies
The condition of having three copies of a given chromosome in each somatic cell rather than the normal number of two.

[tri- + -som(e) + -y.]

tri′some′ n.
tri·so′mic adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

trisomy

(ˈtraɪsəʊmɪ)
n
(Medicine) the condition of having one chromosome of the set represented three times in an otherwise diploid organism, cell, etc. Trisomy of chromosome 21 results in Down's syndrome
[C20: from tri- + (chromo)som(e) + -y3]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

tri•so•my

(ˈtraɪ soʊ mi)

n.
a genetic deviation characterized by the presence of three chromosomes where there are usually a pair.
[1925–30; tri- + -some3 + -y3]
tri•so′mic, adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a celltrisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
Down syndrome, Down's syndrome, mongolianism, mongolism, trisomy 21 - a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation
chromosomal aberration, chromosomal anomaly, chromosonal disorder, chrosomal abnormality - any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

tri·so·my

n. trisomía, trastorno genético por el cual una persona posee tres cromosomas homólogos por célula en lugar de dos (diploide), lo cual causa deformaciones fetales serias.
English-Spanish Medical Dictionary © Farlex 2012

trisomy

n trisomía; — 21 trisomía 21
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
She is the author of the book, "Living with Klinefelter Syndrome, Trisomy X and 47, XYY: www.genetic.org/wp-content/uploads/2016/08/LivingWithKNnefelter SyndromeTrisomyX47XYY.pdf
Due to her Trisomy 18 condition, a DNR had been verbally ordered into her chart by an "attending" physician without parental notice or consent.
This design benefited from studies on Down syndrome patients with partial trisomy 21, whose genomes contained a third copy of portions of chromosome 21.
As for the control samples for Trisomy detection, buccal samples were collected from 11 normal adults (5 females and 6 males) and 4 with Down syndrome (1 female and 3 males).
The background risk for trisomy 21 was high in 32.8% (22/67) of the patients, while 67.2% (45/67) were in the intermediate-risk group.
In this report, we present a male case of mosaic trisomy 9 with higher survival than the mean survival mentioned for this chromosome disorder and no CNS structural abnormality, which shows the wide range of clinical manifestation of this disorder.
Edwards syndrome phenotype results from full, mosaic or partial trisomy 18q.
Most cytogenetic studies in the world indicate that the most frequent type of chromosomal abnormalities in DS is free trisomy 21 with frequency ranges from 93% to 96%, mosaic DS presents a frequency between 2% and 3%, and translocation DS presents a frequency ranges from 2% to 5%.[sup][10] However, these values show a geographical variation from the Eastern to the Western countries.
(3,6,9) Although the laboratories use somewhat different techniques, all of them share very high sensitivity and specificity for detection of trisomy 21 (TABLE 1).
The primary outcome was the area under the receiver-operating-characteristic (ROC) curve for trisomy 21.