The experiments indicated that when dectin-1 recognizes tropomyosin
in house dust mites, shrimp or other common allergy-triggering species it suppresses airway cells' production of an immune molecule, IL-33, which otherwise would promote an allergic response by immune cells.
Gene Ae1 was observed a higher expression in antler mesenchyme of male reindeer, and shared a high homology (99%) of Bos taurus tropomyosin
4 (TPM4), which is one of the four identified tropomyosin
(TPM1, TPM2, TPM3, TPM4) involved in the regulation of muscle contraction and cell membrane transport (Spinner et al.
Peroxiredoxins and tropomyosins
as plasma biomarkers for lung cancer and asbestos exposure.
ICC Gene Gene name Proportion of cases HCM MYBPC3 Myosin binding protein C, 15%-20% cardiac MYH7 Myosin, heavy chain 7 10%-15% TNNI3 Troponin I3, cardiac type [congruent to] 2% TNNT2 Troponin T2, cardiac type [congruent to] 2% TPM1 Tropomyosin
1 (alpha) [congruent to] 1.
Application of recombinant elastin and small GTPase RhoA activation by tropomyosin
allowed correcting the process of actin filament formation .
No band was found at about 37 kDa, corresponding to the Mr of tropomyosin
has acquired from VM Pharma LLC of VM-902A, a first-in-class, allosteric selective tropomyosin
receptor kinase A inhibitor, as well as the backup compounds and associated intellectual property for the potential treatment of chronic pain, the company said.
Abbreviations: EML4, echinoderm microtubule-associated protein-like 4; KIF5B, kinesin family member 5B; KLC1, kinesin light chain 1; TFG, tropomyosin
receptor kinase-fused gene.
detection of major shrimp allergen tropomyosin
The putative heat stable proteins identified were myosin light chain (MLC), actin, tropomyosin
(TPM), troponin T (TnT), myoglobin, and creatine kinase.
Novogen will continue to explore applications of the same technology platform in a range of other clinical indications including glioblastoma, along with its anti- tropomyosin
drug technology in the areas of prostate cancer, melanoma and neuroblastoma.
That component is the microfilament, a series of filaments made up of inter-woven strands of two proteins, actin and tropomyosin