Tuberculosis is a disease caused by bacterium so-called Mycobacterium tuberculosis, which is mainly acquired by inhalation of infectious droplet containing viable tubercle bacilli
This form of the disease, also known as warty TB, occurs due to exogenous inoculation of tubercle bacilli
in a previously sensitised individual with good immunity.
2] The various modes of reaction of the skin to the presence of tubercle bacilli
are determined by the sensitization status of the host to the mycobacterial antigens, cellular immunity, route of infection, the bacillary inoculums and the pathogenicity of the infecting mycobacterial strain.
8 Greenwood and Fox in 1973 on "a comparison of methods for staining tubercle bacilli
in histological sections" showed 33 out of 70 (47%) tuberculous morphology cases being positive for AFB on ZN staining.
The pathologist's exquisite passion for detail in medical diagnosis and the quality of patient care, hallmarks of pathology, are evident from the ARCHIVES' very first edition; in fact, a separate section of the first edition was titled "Laboratory and Technical Notes" and included an article discussing a control method for staining smears for tubercle bacilli
ILT results from tubercle bacilli
gaining access to the portal vein from a microscopic or small tubercular focus in the bowel.
Robert Koch, soon after his discovery of the tubercle bacilli
, unsuccessfully offered tuberculin as a vaccine.
Neither tubercle bacilli
nor parasites were present.
1 It has a wide array of clinical spectrum depend- ing upon the mode of infection, immune status of the host or history of previous sensitization to tubercle bacilli
Gene mutations of 214 drug-resistant tubercle bacilli
, Zhejiang Province, China, 2011-2012 Drug Mutant points Mutant times Mutant times Total no.
In resource-poor countries, like India, which is located in tuberculosis-endemic zone, all cases of cervical lymphadenopathy are traditionally considered a tuberculous aetiology, unless proved otherwise, as tubercle bacilli
are the most common offending agent of cervical lymphadenopathy (1).
Infection control consists in taking precautions in order to reduce the transmission of the tubercle bacilli
, which are disseminated in air by TB coughing patients.