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 (to͞o′mər-ə-jĕn′ĭk, tyo͞o′-)
Capable of causing tumors.

tu′mor·i·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌtjuːmərɪˈdʒɛnɪk) or


causing or tending to cause tumours relating to the development of tumours
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌtu mər ɪˈdʒɛn ɪk, ˌtyu-)

(of cells or a substance) capable of producing tumors.
tu`mor•i•ge•nic′i•ty (-dʒəˈnɪs ɪ ti) n.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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References in periodicals archive ?
Whether to regulate stem cells by affecting their reprogramming, self-renewal, or differentiation, or to better understand mechanism of cancers by targeting tumorigenic signaling nodes, finding the right small molecule is of vital importance to the success of a research project.
Accordingly, elevated NF[kappa]B signaling in IECs enhances WNT signaling and causes a tumorigenic cell reprogramming process, which leads to the onset of SC-like cells with tumor initiation capacity.
During the tumorigenic process the signaling is deregulated, thus allowing the mammary epithelium to expand, proliferate, and invade neighboring tissue (hyperplasia) (MIHEVC & DOVC, 2013).
The results show that the tumorigenic potential of the cGMP manufactured ISC-hpNSC is negligible with no detectable undifferentiated pluripotent stem cells, providing additional assurance to their clinical translation, the company said.
Does Vanicream contain a tumorigenic ingredient comparable to mineral oil?
(1,2) Overall changes in cell surface glycoconjugates are also evident in studies on the differences in lectin binding and lectin-induced agglutination of cancer cells with a focus on the facts showing that lectin-resistant cancer cells acquire reduced tumorigenic and/or metastatic potentials as compared with the parental malignant cells.
Moreover, clinical applications require subsequent redifferentiation into a specific cell type, and undifferentiated iPSCs maybecome tumorigenic by incomplete differentiation of iPSCs.
In addition, BMI1 (polycomb protein family member) involved in stem cell self-renewal and cancer stem cell maintenance [10] is also significantly downregulated (Figure 3(a)), which seems to reflect in tumorigenic potential of U87 cells in the presence of AR-A 014418 (GSK3beta inhibitor) but not with Akt inhibitor studied using protocol of soft agar assay (Figure 3(b)), suggesting that the tyrosine phosphorylation of GSK3beta kinase is critical in regulating the colony formation (Figure 5(c)).
MNU-MECs (WPE1-NB26 cells), derived from second generation tumors formed in nude mice by MNU-transformed RWPE-1 cells (10 [micro]g/mL MNU for 1 hr for four cycles), are tumorigenic in vivo (Webber et al.
Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis.
This prevents telomeres from shortening and extends the life of these tumorigenic cells -- a significant contributor to cancer progression.
A further level of complexity to the understanding of cancer biology comes from the knowledge that the neoplastic cell populations within tumors comprise heterogeneous cell populations, in which cells having different tumorigenic potential coinhabit single tumors.