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A longitudinal fold of the intestinal wall in certain invertebrates that increases the absorptive and digestive surface area of the intestine.

[Greek tuphlos, blind + Greek sōlēn, pipe.]


(in certain animals such as molluscs, annelids, and ascidians) a fold in the intestine or inner wall of the intestine
References in periodicals archive ?
Only one epithelial fold (consisting of columnar epithelial cells with microvilli), known as the typhlosole, is present, where an abundance of larval connective tissue is located.
The major typhlosole (mt) leaves the opening of the intestine and leads anteriorly to the floor of the stomach, winding gradually to the left, where it penetrates into orifice ddd1.
The gut varies" among some worms, she wrote in 1971, "from having a simple groove opposite the typhlosole .