Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.


A high-velocity centrifuge used in the separation of colloidal or submicroscopic particles.

ul′tra·cen·trif′u·gal (-trĭf′yə-gəl, -trĭf′ə-gəl) adj.
ul′tra·cen·trif′u·gal·ly adv.
ul′tra·cen′tri·fu·ga′tion (-fyo͝o-gā′shən) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ultracentrifugation - centrifugation at very high speedsultracentrifugation - centrifugation at very high speeds  
centrifugation - the process of separating substances of different densities by the use of a centrifuge
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
To improve exosome concentration and its quality, several technologies have been developed for exosome purification, among which ultracentrifugation and microfiltration, size exclusion chromatography(SEC), and immunoaffinity capture are favored.
Until recently, the primary methods of assessing a patient's sdLDL-C levels were based on the laborious and time-consuming ultracentrifugation and electrophoresis methods.
In contrasts to above finding literature Kamezaki F et al have concluded that direct measuring LCLc methods over estimates, rather than underestimates LDLc results.20 Chotkowska et al have also highlighted mLDLc methods once compared with gold standard technique of ultracentrifugation to demonstrate a positive bias in comparison to Friedewald's equation.21 Taken together the contrasts in literature with regards to methodologies over and underestimating triglycerides, possible explanation could be: First of all, as the triglyceridemia affects LDLc measures in calculated methods which is evident by the use of different factors to manage VLDL in serum triglyceride calculation, so calculated methods are inherently biased to the presence of triglyceride adjustment.22,23
Based on the size and density of exosomes, we can collect exosomes by ultracentrifugation at 20,000 xg .
Lipoproteins are classified by ultracentrifugation into five major types, with increasing density and decreasing size: chylomicrons (CMs), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL).
As previously reported [32], the tube-length distribution range can be controlled by ultracentrifugation of the SWCNT dispersion.
We obtained a collection rate of over 99 percent, surpassing ultracentrifugation as well as other methods that are currently being used in the field."
F4370), concentrated by ultracentrifugation and purified by sucrose gradient ultracentrifugation.
To isolate the specific signal for chylomicrons from other contaminants that may cause false-positive identification of a chylous effusion, lipid analysis can be performed on fractions of the body fluid after ultracentrifugation that separates the more dense HDL/LDL fraction (the HL fraction, density > 1.006 g/L) from the less dense VLDL/chylomicron fraction (VL fraction, density <1.006 g/L) (7).
Beckman Coulter Life Sciences returns analytical ultracentrifugation (AUC) to the center of protein research and macromolecule characterization with the next-generation Optima AUC.
Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles