The decision evoked considerable surprise in the shipbuilding industry because South Korean companies previously had built most large containerships, and CMA CGM's awarding of the order indicated that China was making substantial progress at building ultralarge
container vessels with the latest navigation, communication, and environmental- and energy-management capabilities.
Caplacizumab is a bivalent anti-vWF Nanobody and blocks the interaction of ultralarge
von Willebrand Factor (vWF) multimers with platelets and, therefore, has an immediate effect on platelet adhesion and the ensuing formation and accumulation of the micro-clots that cause the severe thrombocytopenia, tissue ischemia and organ dysfunction in aTTP, according to the company.
Hyeon, Fabrication of Novel Mesocellular Carbon Foams with Uniform Ultralarge
Thrombotic events exceed the hemorrhagic complications in MPN which occur mainly due to depletion of ultralarge
von Willebrand factor (VWF) multimers by thrombocytosis leading to acquired von Willebrand syndrome (VWS) and altered platelet function [17,19].
The development of space membrane structures drives the construction technology of ultralarge
aerospace structures; consequently, the potential for damage to large membrane structures can be expected to increase in future aerospace projects.
Nolasco et al., "ADAMTS-13 rapidly cleaves newly secreted ultralarge
von Willebrand factor multimers on the endothelial surface under flowing conditions," Blood, vol.
VWF molecules are produced and secreted with different sizes, ranging from dimers to ultralarge
(UL) multimers (up to 100 monomers).
On the other hand, neutrophils also release the protease ADAMTS13, which cleaves hyperactive ultralarge
von-Willebrand-factor and, thus, reduces acute cerebral inflammation after ischemic stroke .
In its latest results announcement, the firm said demand for its ultralarge
format touch screens in particular is driving the company's expansion.
It is largely controlled by about 15 European and Asian operators that have pooled their operations through alliances, sharing networks and port calls and using ultralarge
container ships that redraw the scale of international shipping.
HHICPhil's Subic Shipyard, which sits on a 300hectare area within the Freeport, features an ultralarge
dock (550 meters in length, 135 meters in width), ultralarge
gantry cranes and automated assembly lines with 600,000 deadweight tonnage (DWT) of annual shipbuilding capacity.