A cloud-compatible bioinformatics pipeline for ultrarapid
pathogen identification from next-generation sequencing of clinical samples.
Some women are ultrarapid
metabolizers of codeine because of high levels of CYP2D6, resulting in higher concentrations of morphine in their breast milk and their breast fed newborn.
Duplication of the cytochrome P450 2D6 gene resulting in up to 13 copies in some individuals explains the ultrarapid
metabolizer phenotype observed for a variety of drugs in Northern European and Ethiopian human populations.
2013, Study of reliable rapid and ultrarapid
static GNSS surveying for determination of the coordinates of control points in obstructed conditions.
2015) Evidence for a Shared Mechanism in the Formation of Urea-Induced Kinetic and Equilibrium Intermediates of Horse Apomyoglobin from Ultrarapid
Differences in CYP2D6 alleles can result in significant differences in handling of opiates because the activity level of the CYP2D6 enzyme is determined by the combination of alleles that each patient has, ranging from poor to ultrarapid
A common novel CYP2C19 gene variant causes ultrarapid
drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.
Direct activation of the Mauthner cell by electric field pulses drives ultrarapid
Individuals carriers of two inactive CYP2C19 alleles are predicted to be gPMs, while carriers of *1/*17 or *17/*17 genotypes are predicted ultrarapid
Blind evaluation of the microwave-accelerated metal-enhanced fluorescence ultrarapid
and sensitive Chlamydia trachomatis test by use of clinical samples," Journal of Clinical Microbiology, vol.
Thus, the population can be classified into Extensive Metabolisers (EM, individuals with normal capacity), Poor Metabolisers (PM, individuals with reduced/null metabolic activity), and Ultrarapid
Metabolisers (UM, individuals with a higherthan-normal metabolic activity).
Clinical Pharmacogenomics Implementation Consortium (CPIC) guidelines recommend against administration of codeine to ultrarapid
CYP2D6 metabolizers because of higher risk of adverse drug reactions due to morphine intoxication.