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Related to uricosuric: Uricosuric agents, probenecid, pegloticase


Promoting the excretion of uric acid in the urine.

[From uric + uric.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biology) increasing or promoting the excretion of uric acid in urine
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Adj.1.uricosuric - acting to increase the excretion of uric acid in the urine
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References in periodicals archive ?
Traditionally used for rheumatism, this is another anti-inflammatory agent with diuretic (urine excretion) and uricosuric (urine acid excretion) activity that offers a blood purifying effect.
Losartan has uricosuric effects and lowers uric acid levels, a property that is unique to losartan of the angiotensin receptor blockers (ARBs) that have been studied.
The dosage change may be considered if the administered dosage is not effective, or uricosuric agents such as probenecid or benzobromaron or new xanthine oxidase inhibitor febuxostat are added to the treatment.
Probenecid, uricosuric drug in the treatment of gout, interferes with renal excretion of steroid glucuronides.
Subjects under use of uricosuric drugs, with body mass index [greater than or equal to] 30, glomerular filtration rate [less than or equal to] 70 mL/min were not eligible for randomization.
Available US Food and Drug Administration (FDA)-approved options for lowering sUA include xanthine oxidase inhibitors (allopurinol and febuxostat) that prevent production of uric acid; a uricosuric agent (probenecid) that increases uric acid output in urine; and a uric acid-specific enzyme (pegloticase) that converts uric acid to allantoin.
(12) Patients who used antidiabetic drugs, insulin, antilipemic drugs, uricosuric drugs, steroids, and oral contraceptives were omitted from the study.
Usually, estrogens increase the uric acid excretion due to its uricosuric action; the estrogen decrease and the insulin resistance reduce the uric acid clearance, favoring hyperuricemia [6].
The commonly used urate-lowering agents in clinical practice include two classes: urate production inhibitors and uricosuric agents.
In addition, hyperuricemia was also noted and controlled by uricosuric agents postoperatively.
Subjects who are on non-steroidal anti-inflammatory drugs (NSAID's) or xanthine oxidase inhibitors or uricosuric agents for last 14 days.
Currently, XOD inhibitors (allopurinol (AP) and febuxostat) and uricosuric agents (benzbromarone and probenecid) are used as antihyperuricemia drugs in clinical practice [9].