uridine


Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.

u·ri·dine

 (yo͝or′ĭ-dēn′)
n.
A nucleoside, C9H12N2O6, that is composed of uracil and ribose, is a component of RNA, and plays a role in regulating many physiological processes.

uridine

(ˈjʊərɪˌdiːn)
n
(Biochemistry) biochem a nucleoside present in all living cells in a combined form, esp in RNA
[C20: from uro-1 + -ide + -ine2]

u•ri•dine

(ˈyʊər ɪˌdin, -dɪn)

n.
a ribonucleoside composed of ribose and uracil.
[< German Uridin (1910); see uracil, -idine]
Translations
uridine
References in periodicals archive ?
Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and Factor XI deficiency in Holstein cows reared in Turkey.
Therefore, by aiding nerve cell functions related to synapses uridine is believed to help preserve brain function and protect it from degeneration.
[17] Decreased hormone levels can cause prolonged unconjugated hyperbilirubinemia and appears to be associated with the delayed maturation of hepatic uridine diphosphate glucuronyl transferase (UDPG-T) enzyme activity.
The low concentration of [sup.13]C labeled uridine and high concentrations of labeled AXP as well as the nucleotide sugars from the [U-[sup.13]C]-glucose in the media of BT474 cells may be a consequence of the seemingly higher aerobic TCA activity seen in these cells compared to the other three lines.
Further, these RNAs were present in both sense and antisense orientation and possessed a 5' Uridine bias, suggesting their processing by RNase III enzyme.
Characterization of bile acid uridine 5'-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes," The Journal of Clinical Investigation, vol.
Four reference substances (guanosine, adenosine, uracil, and adenine) were purchased from the National Institutes for Food and Drug Control (China), and uridine was purchased from the Nanchang Beta Biotechnology Co.
Sixty-five metabolites were quantified, six of which could be related to early post-injury degenerative changes: isobutyrate, glucose, hydroxyprolyne, asparagine, serine, and uridine. Most of them were associated with the hypoxic and acidotic conditions of an injured and inflamed joint.
Glycine and uridine prevent D-galactosamine hepatotoxicity in the rat: role of Kupffer cells.
Neonatal physiologic jaundice can be a result of increased bilirubin production secondary to accelerated destruction of erythrocytes or decreased excretory capacity secondary to low levels of ligandin which is a binding protein for bilirubin in hepatocytes and low activity of bilirubin-conjugating enzyme uridine diphosphoglucuronyltransferase (UDPGT).
Gilbert syndrome (GS, MIM #143500) is characterized by fluctuating mild, unconjugated hyperbilirubinemia <85 [micro]mol/L and is caused by mutations in the bilirubin uridine diphosphate (UDP)-glucuronosyltransferase gene ( UGT1A1 ).[sup][1] Dubin-Johnson syndrome (DJS, MIM #237500) is characterized by fluctuating mild, predominantly conjugated hyperbilirubinemia and is caused by mutations in the ATP-binding cassette subfamily C member 2 gene ( ABCC2 ).[sup][2] This report described the unusual features encountered in a Chinese family that was genetically confirmed to have both DJS and GS.