He proposed that the upper 80% of the vagina is derived from Mullerian epithelium and the lower 20% derived from urogenital sinus
Second, in the urogenital sinus
and urogenital tubercle, it acts as a prohormone for DHT, the third hormone of male virilization.
(1,5) The lower or distal urogenital tract is derived from the embryonic urogenital sinus
and is endoderm in its origin.
During the evacuation of the contrast medium, there was reflux into the cystic mass with elimination through the two orifices, which made it possible to affirm the existence of a urogenital sinus
thus explaining the communication between the urinary and genital tracts.
A misalignment between the termination of the cloacal membrane and its relationship with the developing genital tubercle and urogenital sinus
has been reported (1).
The bladder and urethra are derived from the primitive urogenital sinus
. This formation continues with the prostate in the 3rd month.
Transverse vaginal septum is a rare condition that results from incomplete fusion between the vaginal components of the mullerian ducts and the urogenital sinus
. Its incidence is approximately 1 in 30,000 to 1 in 80,000 women (Figure 1).
Hymen is formed from the epithelial lining of paramesonephric ducts and urogenital sinus
at vestibulo vaginal junction.
Due to the future lower pole ureter separating from the Wolffian duct earlier, it migrates superiorly and laterally as the urogenital sinus
grows and becomes the upper pole moiety.
Case 2 (IV6) was a Turkish female presenting with clitoromegaly, complete labial fusion, and single urogenital sinus
at birth (Prader III).
Sinowatz (2010) describes that the vagina has two origins: one anterior, derived from the paramesonephric ducts and one posterior derived from the urogenital sinus
. However, the microstructure of the vagina is not described.
It is true that the exact etiology of such anomalies is still unknown, but it has been established that they have their origin in a mesonephric (Wolffian duct) anomaly.[sup] The mesonephric anomaly with the absence of the Wolffian duct opening into the urogenital sinus
and therefore of the ureteral bud sprouting, justifies the blind vagina and unilateral renal agenesis.