urokinase


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Related to urokinase: streptokinase

u·ro·ki·nase

 (yo͝or′ō-kī′nās, -nāz)
n.
An enzyme originally found in human urine that catalyzes the conversion of plasminogen to plasmin and is used in medicine to dissolve blood clots.

urokinase

(ˌjʊərəʊˈkaɪneɪz)
n
(Biochemistry) a biochemical catalyst present in urine and the blood stream

u•ro•ki•nase

(ˌyʊər əˈkaɪ neɪs, -neɪz)

n.
an enzyme, present in the blood and urine of mammals, that activates plasminogen and is used medicinally to dissolve blood clots.
[1955–60]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.urokinase - protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis
peptidase, protease, proteinase, proteolytic enzyme - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis
Translations

ur·o·ki·nase

n. urocinasa, enzima presente en la orina que se emplea en la disolución de coágulos.

urokinase

n uroquinasa (INN), urokinasa or urocinasa
References in periodicals archive ?
Moreover, the patient completed another two cycles of closed drainage on both sides of the chest due to left pneumothorax and right empyema, and a daily urokinase dose of 100,000 U was injected to accelerate the elimination of pus.
May, "Urokinase receptor: a molecular organizer in cellular communication," Current Opinion in Cell Biology, vol.
For urokinase, the use of urokinase has been shown to transform plasminogen to plasmin, a strong serine proteinase involved in the degradation of fibrinogen to several fragments.
Our group recently reported that the [beta]3 subunit of integrin was essential for the action of podocyte membrane protein urokinase plasminogen activator receptor (uPAR), which eventually led to effacement of the FPs and proteinuria [77].
Fuhrman, "The urokinase system in the pathogenesis of atherosclerosis," Atherosclerosis, vol.
Gurewich, "Activation of plasminogen by single-chain urokinase or by two-chain urokinase-a demonstration that single-chain urokinase has a low catalytic activity (pro-urokinase)," Blood, vol.
Treatment of free-flowing tuberculous pleurisy with intrapleural urokinase. Int J Tuberc Lung Dis.
The "Investigation Report on China's Urokinase Market, 2019-2023" report has been added to ResearchAndMarkets.com's offering.
Anticoagulation must be discontinued when thrombolytic therapy is administered, especially if using streptokinase or urokinase. This is not an absolute requirement for rt-PA.
Soluble urokinase plasminogen activator receptor (suPAR), the soluble form of uPAR, has emerged as a valuable indicator of the activation state of the immune system.
Ten minutes into reanimation a bolus of 2.000.000 IU of urokinase was administered via a central venous catheter but no response was obtained.
Prognostic implications of the co-detection of the urokinase plasminogen activator system and osteopontin in patients with non-small-cell lung cancer undergoing radiotherapy and correlation with gross tumor volume.