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Overactivity or irritability of the vagus nerve, adversely affecting function of the blood vessels, stomach, and muscles.

va′go·ton′ic (-tŏn′ĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Pathology) of or relating to vagotonia
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
However, the vagotonic effect of cholinesterase inhibitors might also protect the heart against ischemia and dysarrhythmias.
Propofol causes hypotension due to its vagotonic effect and fentanyl inhibits baroreceptor reflex.
The onset of asystole during expiration may be an extreme example of a normal respirophasic sinus arrhythmia in a vagotonic subject; however, that does not appear to be a sufficient explanation, as asystole could not be reproduced by breath-holding without concomitant use of the inhalers.
The cardiac glycosides in Nerium oleander have vagotonic effects, resulting in bradycardia and heart block.