"This caused Alannah to develop varices
, which are dilated blood vessels in the oesophagus that can be life-threatening if they rupture.
Belapectin is the first drug to show positive results in a clinical trial in patients with compensated NASH cirrhosis without esophageal varices
, and it is with great optimism that we anticipate a fourth quarter launch of this very important trial."
Keywords: Chronic liver disease, Esophageal varices
, SAAG, Upper GI endoscopy.
and ascites occur after portal pressure exceeds 10-12 mm Hg (1-3).
Objective: To determine the safety and efficacy of N-butyl 2-cyanoacrylate in bleeding gastric varices
Upper gastrointestinal endoscopic examination revealed grade 3 esophageal and fundal varices
(Figure 1a, 1b).
Endoscopic therapy is usually the initial treatment option for bleeding duodenal varices
, but it is not always feasible or successful (2).
Among the various possible evaluations, in clinical practice, the assessment of the presence of varices
and of the extent of fibrosis in the liver and spleen are certainly the most important.
Upon endoscopy, most patients are found to harbour esophageal varices
while in a minority of patients, gastric varices
are the primary sites of bleeding.
Approximately 50% of the patients develop esophageal varices
while a small percentage develops complications in the other part of the gastrointestinal tract like ectopic varices
in the small bowel [4, 5].