Higher nucleotide identities were found among ECTVs (99.97%-99.99%) and between VARV-Garcia1966 (variola minor) and VARV-India1967 (variola major
"At that time Henry said 'I'm not going to allow you to work with variola major
, which is the nasty smallpox, you're going to do this experimental work with variola minor'.
Improvements in health have bettered the human condition enormously, and Pinker tells us that his favourite sentence in the whole English language comes from Wikipedia: "Smallpox was an infectious disease caused by either of two virus variants, Variola major
and Variola minor." The word was is what he likes.
Categories Diseases/Agents A Anthrax (Bacillus anthracis), Botulism (Clostridium botulinum), Plague (Yersinia pestis), Smallpox (Variola major
), Tularemia (Francisella tularensis), Viral hemorrhagic fevers B Brucellosis (Brucella species), epsilon toxin of Clostridium perfringens, food safety threats (e.g., Salmonella species, Escherichia coli O157:H7, Shigella), Glanders (Burkholderia mallei), melioidosis (Burkholderia pseudomallei), Psittacosis (Chlamydia psittaci), Q fever (Coxiella burnetii), ricin toxin from Ricinus communis (castor beans),Staphylococcal enterotoxin B, Typhus fever (Rickettsia prowazekii), viral encephalitis [alphaviruses (e.g.
The report by NTI also stated North Korea was capable of indigenously producing other agents of biological warfare including Variola major
(smallpox), Francisella tularensis (rabbit fever), and Bunyaviridae Hantavirus (Korean hemorrhagic fever).
Caused by the variola major
virus, smallpox inflicted great pain on victims, beginning with fever, nausea and other flu-like symptoms before leading to lesions on the face and body.
Classification of biological agents (13) Agents Group A Agents Group B Plague (Yersinia pestis) Brucellosis (Brucella species) Botulism (Clostridium botulinum) Ricin toxin (Ricinus communis) Anthrax (Bacillus anthracis) Shigella Smallpox (Variola major
) Q fever (Coxiella burnetii) Tularemia (Francisella tularensis) Cholera (Vibrio cholerae) Viral Hemorrhagic Fevers (Lassa, Glanders (Burkholderia mallei) Machupo, Ebola) Escherichia coli O157:H7 Salmonella Agents Group C Yellow fever Nipah virus Tick encephalitis viruses Hemorrhagic tick fever Multi-resistant tuberculosis Hanta virus Table 2.
On the other hand, Langmuir, Usher and the CDC were surely right to emphasize the great difficulty eradication would actually entail, especially in East Bengal, and it's no an accident that the very last cases on earth of Variola major
were stamped out in Bangladesh--the former East Pakistan--late in 1975.
Evidence is presented in four chapters concerning the 1763 introduction of smallpox (Variola major
) via tainted blankets to Native groups around Fort Pitt; the 1832 forced transport of Choctaw people into the midst of a cholera (Vibrio cholerae) epidemic; an 1837 epidemic of hemorrhagic smallpox (Variola vera) along the Upper Missouri River; and the 1847 poisoning of Native people in the Oregon territory.
His mother, Eleanor McMillan, was a graduate of Chatham Hospital School of Nursing and worked on the smallpox wards at Henry Ford Hospital during North America's last outbreak of variola major
in Detroit and Windsor in 1924; his uncle, William McMillan, a physician, would become the ranking Liberal Member of Parliament in the 1960s.
Category A biological agents include: Variola major
(smallpox), Bacillus anthracis (anthrax), Yersinia pestis (plague), Clostridium botulinum (botulism), Francisella tularensis (tularemia) and filoviruses and arena viruses (such as Ebola and Lassa virus which result in viral hemorrhagic fever) (CDC 200511).
Jonathan Tucker described the difference thus: Variola major
caused a serious disease that killed between 10 percent and 30 percent of its victims, whereas variola minor gave rise to a much milder illness called alastrim, with a case mortality rate of less than 1 percent.