Puccinelli et al., "Detection of carotid adventitial vasa vasorum
and plaque vascularization with ultrasound cadence contrast pulse sequencing technique and echo-contrast agent," Stroke, vol.
This is an interesting and plausible explanation that emphasizes the proatherosclerotic properties of periadventitial fat; however, the authors did not address whether the adventitia and vasa vasorum
, 2 other anatomic factors that play a role in atherosclerosis, are altered in intra-myocardial arteries.
Background: Accumulating evidence indicates a potential role of adventitial vasa vasorum
(VV) dysfunction in the pathophysiology of restenosis.
The infectious agent can either travel through the blood stream and harbor in the vasa vasorum
of the arterial wall or implant on damaged intima, ulcerated arteriosclerotic plaques, or mural thrombus.
In swine, adventitial (vasa vasorum
) angiogenesis occurs within 3 days after experimental coronary angioplasty, and regression of adventitial vessels correlates with arterial narrowing, suggesting that the adventitial microvasculature greatly influences arterial remodeling.
To the Editor: I reviewed the article Quantification of adventitial vasa vasorum
(VV) vascularization in double-injury restenotic arteries by Meng et al .
The neutrophil activation and perivascular infiltration in the vessel wall lead to degeneration and occlusion of the vasa vasorum
. Therefore, the main difference between true aneurysm and pseudoaneurysm is the lack of an adventitia in pseudoaneurysm, where the whole wall is lacerated.,
The authors proposed that occlusive thrombi of the umbilical arteries led to the necrosis of the inner layer of the media because of the lack of vasa vasorum
. This is consistent with our case.
Pathological examination suggests that MRAAs develop from septic emboli that penetrate the vasa vasorum
, seeding adventitial inflammation and dilation of the weakened arterial wall .
Esta patologia afecta el vasa vasorum
de la aorta, principalmente la porcion ascendente, lo que causa una necrosis y destruccion de la capa media de la arteria, asi como un aneurisma sacular .
The second mechanism is by vasculitis in the vasa vasorum
of the cochlear nerve by a secondary immune mechanism.