crisis

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Related to vaso-occlusive crisis: sickle-cell disease, acute chest syndrome, Sickle cell crisis

cri·sis

 (krī′sĭs)
n. pl. cri·ses (-sēz)
1. A crucial or decisive point or situation, especially a difficult or unstable situation involving an impending change.
2. A sudden change in the course of a disease or fever, toward either improvement or deterioration.
3. An emotionally stressful event or traumatic change in a person's life.
4. A point in a story or drama when a conflict reaches its highest tension and must be resolved.

[Middle English, from Latin, judgment, from Greek krisis, from krīnein, to separate, judge; see krei- in Indo-European roots.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

crisis

(ˈkraɪsɪs)
n, pl -ses (-siːz)
1. a crucial stage or turning point in the course of something, esp in a sequence of events or a disease
2. an unstable period, esp one of extreme trouble or danger in politics, economics, etc
3. (Pathology) pathol a sudden change, for better or worse, in the course of a disease. Also (archaic): crise
[C15: from Latin: decision, from Greek krisis, from krinein to decide]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

cri•sis

(ˈkraɪ sɪs)

n., pl. -ses (-sēz).
1. a turning point, as in a sequence of events, for better or for worse.
2. a condition of instability, as in international relations, that leads to a decisive change.
3. a personal tragedy, emotional upheaval, or the like.
4.
a. the point in the course of a serious disease at which a decisive change occurs, leading to recovery or to death.
b. the change itself.
5. the point, as in a play, at which the antagonistic elements confront each other.
[1375–1425; late Middle English < Latin < Greek krísis decision =kri- variant s. of krinein to decide, separate + -sis -sis]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

crisis

An incident or situation involving a threat to the United States, its territories, citizens, military forces, possessions, or vital interests that develops rapidly and creates a condition of such diplomatic, economic, political, or military importance that commitment of US military forces and resources is contemplated in order to achieve national objectives.
Dictionary of Military and Associated Terms. US Department of Defense 2005.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.crisis - an unstable situation of extreme danger or difficultycrisis - an unstable situation of extreme danger or difficulty; "they went bankrupt during the economic crisis"
Dunkirk - a crisis in which a desperate effort is the only alternative to defeat; "the Russians had to pull off a Dunkirk to get out of there"
exigency - a pressing or urgent situation; "the health-care exigency"
critical point, crossroads, juncture - a crisis situation or point in time when a critical decision must be made; "at that juncture he had no idea what to do"; "he must be made to realize that the company stands at a critical point"
situation - a complex or critical or unusual difficulty; "the dangerous situation developed suddenly"; "that's quite a situation"; "no human situation is simple"
economic crisis, slump, depression - a long-term economic state characterized by unemployment and low prices and low levels of trade and investment
2.crisis - a crucial stage or turning point in the course of something; "after the crisis the patient either dies or gets better"
juncture, occasion - an event that occurs at a critical time; "at such junctures he always had an impulse to leave"; "it was needed only on special occasions"
emergency, exigency, pinch - a sudden unforeseen crisis (usually involving danger) that requires immediate action; "he never knew what to do in an emergency"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.

crisis

noun
1. emergency, plight, catastrophe, predicament, pass, trouble, disaster, mess, dilemma, strait, deep water, meltdown (informal), extremity, quandary, dire straits, exigency, critical situation Strikes worsened the country's economic crisis.
2. critical point, climax, point of no return, height, confrontation, crunch (informal), turning point, culmination, crux, moment of truth, climacteric The anxiety that had been building within him reached a crisis.
Collins Thesaurus of the English Language – Complete and Unabridged 2nd Edition. 2002 © HarperCollins Publishers 1995, 2002

crisis

noun
1. A decisive point:
2. A highly volatile dangerous situation requiring immediate remedial action:
The American Heritage® Roget's Thesaurus. Copyright © 2013, 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations
أَزْمَةأزْمـهضائِقَـه، وَقت الأزمَـه
krizekritická situace
krisekrisetilstandvendepunkt
kriisi
kriza
krízisválság
hættuástandkreppaumhvörf; hættuástand; krísa
クライシス危機重大局面
위기
krizėpavojussukrėtimas
kritiska situācijakrīze
kriza
kris
ช่วงวิกฤต
cuộc khủng hoảng

crisis

[ˈkraɪsɪs]
A. N (crises (pl)) [ˈkraɪsiːz]crisis f inv (Med) → punto m crítico
to come to a crisisentrar en crisis
we've got a crisis on our handsestamos enfrentándonos a una crisis
B. CPD crisis centre (Brit) crisis center (US) N (for disaster) → centro m coordinador de rescate; (for personal help) → teléfono m de la esperanza; (for battered women) → centro m de ayuda (a las mujeres maltratadas)
crisis management Ngestión f de crisis
Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

crisis

[ˈkraɪsɪs] [crises] [ˈkraɪsiːz] (pl) ncrise f
economic crisis → crise f économique
financial crisis → crise f financière
hostage crisis → crise f des otages
refugee crisis → crise f des réfugiés
budget crisis → crise f budgétaire
energy crisis → crise f de l'énergie
to be in crisis → être en crise
in times of crisis → en temps de crise crisis management, crisis of confidence, identity crisis, Gulf Crisiscrisis management ngestion f de crisecrisis of confidence ncrise f de confiance
Collins English/French Electronic Resource. © HarperCollins Publishers 2005

crisis

n pl <crises> → Krise f (also Med); to reach crisis pointden Höhepunkt erreichen; that was a crisis in his life (= decisive moment)das war ein entscheidender Punkt in seinem Leben; (= emotional crisis)das war eine Krise in seinem Leben; at this time of crisisin dieser krisenreichen or schweren Zeit; in times of crisisin Krisenzeiten

crisis

:
crisis centre
nEinsatzzentrum nt (für Krisenfälle); rape crisisBeratungsstelle f (für Frauen, die Opfer einer Vergewaltigung geworden sind)
crisis management
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

crisis

[ˈkraɪsɪs] n (crises (pl)) [ˈkraɪsiːz]crisi f inv
to come to a crisis → entrare in crisi
we have a crisis on our hands → ci troviamo di fronte a una crisi
Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

crisis

(ˈkraisis) plural ˈcrises (-siːz) noun
1. a deciding moment or turning-point (especially of an illness). Although she is still very ill, she has passed the crisis.
2. a time of great danger or difficulty. a crisis such as the recent flooding; You can rely on her in a crisis.
Kernerman English Multilingual Dictionary © 2006-2013 K Dictionaries Ltd.

crisis

أَزْمَة krize krise Krise κρίση crisis kriisi crise kriza crisi 重大局面 위기 crisis krise kryzys crise кризис kris ช่วงวิกฤต kriz cuộc khủng hoảng 危机
Multilingual Translator © HarperCollins Publishers 2009

crisis

n (pl -ses) crisis f; blast — crisis blástica; identity — crisis de identidad; midlife — crisis de la mediana edad
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
An expert panel report released by the National Heart, Lung, and Blood Institute (NHLBI) (2014) included recommendations for the management of pain in pediatric patients who present with vaso-occlusive crisis. The report emphasized the importance of 1) assessing pain rapidly using self-reported pain scales and observation, 2) assessing previously used analgesics and their effectiveness, and 3) administering analgesic therapy within 30 minutes of triage in the ED.
The sheet included sociodemographic data (age, gender, residency, and nationality), as well as variables related to clinical presentation of SCA, including vaso-occlusive crisis, ACS and bacterial infection.
BMI: body mass index; VOC: vaso-occlusive crisis; ACS: acute chest syndrome; TRV: tricuspid regurgitation velocity; GGO: ground-glass opacification.
The report provides comprehensive information on the therapeutics under development for Vaso-Occlusive Crisis Associated With Sickle Cell Disease, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
With its anti-adhesive properties, sevuparin could thereby offer treatment of the underlying cause of vaso-occlusive crisis (VOC) in SCD patients, with earlier pain relief, shorter hospital stay, reduced need of opioids and improved quality of life.
Management of painful vaso-occlusive crisis of sickle-cell anemia: Consensus opinion.
[6,7,10] Platelet aggregate formation activity is normal in SCD patients in steady state, but abnormally high in each SCD patient with vaso-occlusive crisis. It is a matter of further research that whether increased platelet aggregate formation during acute thrombotic event is primarily responsible for the initiation of the event, or is a secondary phenomenon in response to tissue injury.
The purpose of this study is to (1) test the hypothesis that levels of cfDNA are increased in the plasma of SCD patients in acute painful vaso-occlusive crisis (VOC) compared with steady state situation and to ethnically matched healthy controls, (2) correlate cfDNA levels with other biomarkers known to be elevated in acute sickling crises, and (3) explore the potential use of cfDNA as a biomarker in diagnosis and monitoring SCD and its complications, such as acute pain crisis.
The rule, as it now stands, relates to Vaso-occlusive crisis patients, a common painful complication of sickle cell anaemia that affects around 5,000 people in Bahrain.
Sickle cell disease (SCD) is an autosomal recessive genetic disorder characterised by the Hb S variant of the b-globin gene.4 The most common clinical problem is the painful vaso-occlusive crisis (VOC) resulting as a consequence of intravascular sickling in capillaries and small vessels.
Investigators propose that endocrine organ dysfunctions in SCD patients may be caused by iron overload due to recurrent blood transfusions or disruptions of tissue vitalization during vaso-occlusive crisis and inflammatory mediators (1), (2), (3).