Following peripheral Axotomy, some the dorsal root ganglion(DRG) and ventral horn
neurons undergo a series of retrograde degenerative changes classic that lead to neuronal death (Himes & Tessler, 1989; Vestergaard et al., 1997; Terenghi, 1999; Pierucci & de Oliveira, 2006).
Herein, we first illustrated the temporal astrocyte activation in the spinal ventral horn
at different stages following PNI as well as the neurotrophic expression in the activated astrocytes.
The whole ventral horn
of the spinal cord was photographed at x 10 magnification with Zeiss Axiophot microscope.
To quantify the neuronal damage caused by SCI, MAP2-positive cells per [mm.sup.2] in the ventral horn
of each group were counted (Figure 3(g)), and the results demonstrated that MAP2-positive cells were decreased equally in number at 7 days after SCI in the RGE-treated and vehicle-treated groups when compared with those in pre-SCI animals.
Moreover, Motor neurons are located in the ventral horn
of the spinal cord and control effectors muscles in the periphery.
6-8 individual spinal cord sections were analysed per rat, and the mean of the left and right half of the dorsal and ventral horn
was calculated for each section.
(3) During the 3-5 weeks of gestational age neurulation occurs during which formation of the neural groove, closure of the anterior (25 days) and posterior (27 to 28 days) neuropores, appearance of the ventral horn
cells, formation of anterior and posterior roots and disjunction of the neuroectoderm from the surface ectoderm takes place.
The neuropils of the ganglion stained intensely with anti-GABA, especially at the medial edge of the dorsal horn and the lateral edge of the ventral horn
of the ganglion in male abalone (Fig.
Changes of 5-hydroxytryptamine and tryptophan hydroxylase expression in the ventral horn
of spinal cord.
Microscopic review of the animals' spinal cords at 8 weeks postimplant showed that in many cases, the neural stem cells had migrated up and down the spinal cord and intro the ventral horn
, with 5-7% of the cells differentiating into neurons.
The 5-[HT.sub.2A] receptor is abundant in ventral horn
MNs [37, 38], with variable expression levels depending upon the functional role of the cell.
Severe degenerative changes in the ventral horn
of the spinal cord were identified in 10 of the malformed calves.