verapamil


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ve·rap·a·mil

 (və-răp′ə-mĭl′)
n.
A calcium channel blocker drug, C27H38N2O4, that acts as a coronary vasodilator and is used in its hydrochloride form to treat hypertension and certain cardiac arrhythmias.

[vera(tryl), one of its constituents (from New Latin Vērātrum, hellebore genus; see veratrine) + -pamil, vasodilating drug suffix (perhaps p(ropyl) + am(ino) + (nitr)il(e)).]

verapamil

(vɪˈræpəˌmɪl)
n
(Pharmacology) med a calcium-channel blocker used in the treatment of angina pectoris, hypertension, and some types of irregular heart rhythm

ve•ra•pam•il

(ˌvɪər əˈpæm əl, ˌvɛr-)

n.
a white, crystalline powder, C27H38N2O4, used as a calcium blocker in the treatment of angina and certain arrhythmias.
[1965–70]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.verapamil - a drug (trade names Calan and Isoptin) used as an oral or parenteral calcium blocker in cases of hypertension or congestive heart failure or angina or migraine
calcium blocker, calcium-channel blocker - any of a class of drugs that block the flow of the electrolyte calcium (either in nerve cell conduction or smooth muscle contraction of the heart); has been used in the treatment of angina or arrhythmia or hypertension or migraine
Translations

verapamil

n verapamilo, verapamil m
References in periodicals archive ?
Limited Tenders are invited for Supply of TAB VERAPAMIL HCL 40 MG
In situ single pass intestinal perfusion was used to investigate the absorption sites of three constituents in the small intestine, as well as the influence of drug concentrations, concentrations of P-gp inhibitor verapamil hydrochloride, concentrations of MRP2 inhibitor probenecid, and concentrations of energy inhibitor 2,4-dinitrophenol, in order to discuss the absorption mechanism of the constituents and influent factors (5).
4,5,6,7,8] 5-FU, [9,10&11] Bleomycin, [12&13] Verapamil, [14,15,16,17,18,19] Silicone gel sheet, [20.
Her medication list included aspirin (81 mg daily), pravastatin (80 mg daily), and verapamil (120 mg daily).
You're also more likely to have myalgia if you take other cholesterol-lowering medications called fibrates, calcium channel blockers such as verapamil (Calan, Isoptin), the blood thinner warfarin, cimetidine (Tagamet), which is used to treat reflux disease, and some drugs used to treat heart arrhythmias.
8%) patients had taken verapamil, 7 (50%) patients amlodipine, and 1 (7.
Verapamil, a synthetic papaverine derivative, primarily blocks ICa L but also may have some blocking effect on the ryanodine receptor, both of which may contribute to intracellular calcium overload.
A series of mechanistic studies revealed that 7-O-POM-Q competes with verapamil in binding to the same drug-binding site of the major MDR target, Pgp (P-glycoprotein), and inhibits Pgp-mediated drug efflux with a similar potency as verapamil.
This study was undertaken to compare the effects of extract from fruits of medicinal plant Ammi visnaga which contains natural calcium channel blocker and verapamil on volume and acidity of carbachol induced gastric secretion.
John's wort can reduce the efficacy of a number of prescription drugs, including blood thinners, cancer chemotherapy drugs, cholesterol-lowering statin drugs, immunesuppressing medications, digoxin, and the drug verapamil (Calan[R]).
The sample with verapamil was conducted by the incubation of 30 mcl of cell suspension in 150 mcl of Hank's medium containing [10.
TEHRAN (FNA)- Iranian scientists announced earlier this year that they have successfully synthesized and evaluated a new type of electrochemical sensors to measure verapamil cardiovascular drug.