verapamil


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ve·rap·a·mil

 (və-răp′ə-mĭl′)
n.
A calcium channel blocker drug, C27H38N2O4, that acts as a coronary vasodilator and is used in its hydrochloride form to treat hypertension and certain cardiac arrhythmias.

[vera(tryl), one of its constituents (from New Latin Vērātrum, hellebore genus; see veratrine) + -pamil, vasodilating drug suffix (perhaps p(ropyl) + am(ino) + (nitr)il(e)).]

verapamil

(vɪˈræpəˌmɪl)
n
(Pharmacology) med a calcium-channel blocker used in the treatment of angina pectoris, hypertension, and some types of irregular heart rhythm

ve•ra•pam•il

(ˌvɪər əˈpæm əl, ˌvɛr-)

n.
a white, crystalline powder, C27H38N2O4, used as a calcium blocker in the treatment of angina and certain arrhythmias.
[1965–70]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.verapamil - a drug (trade names Calan and Isoptin) used as an oral or parenteral calcium blocker in cases of hypertension or congestive heart failure or angina or migraine
calcium blocker, calcium-channel blocker - any of a class of drugs that block the flow of the electrolyte calcium (either in nerve cell conduction or smooth muscle contraction of the heart); has been used in the treatment of angina or arrhythmia or hypertension or migraine
Translations

verapamil

n verapamilo, verapamil m
References in periodicals archive ?
Tenders are invited for pharmaceutical products (epinephrine, azithromycin, allopurinol, ammonia, amiodarone, amlodipine, amoxicillin and enzyme inhibitor, atropine, aciclovir, bisoprolol, vancomycin, verapamil, medicinal charcoal, gentamicin, heparin, glucose, dexamethasone, dextran, dexpanthenol, digoxin, diclofenac,
The COA said the BuCor received 99,300 Verapamil tablets for high blood pressure last year, but only 3,450 tablets were actually issued to inmate patients.
Under the amended agreement, Recro Gainesville will continue to supply Teva with Verapamil SR capsules through 2024 and Teva will continue to be Recro Gainesville's exclusive U.S.
Under the terms of the amended agreement, Recro Gainesville will continue to supply Teva with Verapamil SR capsules through 2024 and Teva will continue to be Recro Gainesville's exclusive United States distributor of the product, for which Recro Gainesville is the new drug application holder.
All the anticonvulsants were stopped, and as flunarizine is not available in SA and topiramate could only be obtained through a patient-named motivation, it was decided to start him on verapamil in the interim.
Objective: To evaluate the efficacy of combined use of nitrate and calcium channel blocker (Verapamil) in prevention of radial artery spasm during coronary angiographies.
Mechanical stimulation has been shown to have a strong influence on chondrocyte biosynthetic activity.[2] Furthermore, multiple studies have suggested a regulatory role for intracellular Ca2+ in endochondral ossification, a process that includes chondrocyte proliferation, differentiation, and apoptosis.[3] Based on the above findings, we hypothesized that mechanical stress alone or in combination with the voltage-sensitive Ca2+ channel inhibitor verapamil would stimulate chondrocytes with respect to AGC biosynthesis.
Vagal manoeuvres, beta-blockers, verapamil, and diltiazem are used to end acute episodes of PSVT and to reduce the frequency of chronic episodes.
The clinical picture was suggestive of a CH and the patient was medicated with verapamil 120 mg daily.
A combination of chemotherapeutic agents with multidrug resistance protein (MRP) inhibitors, such as verapamil, has been shown to have an in vivo anticancer synergistic mechanism [19].
In situ single pass intestinal perfusion was used to investigate the absorption sites of three constituents in the small intestine, as well as the influence of drug concentrations, concentrations of P-gp inhibitor verapamil hydrochloride, concentrations of MRP2 inhibitor probenecid, and concentrations of energy inhibitor 2,4-dinitrophenol, in order to discuss the absorption mechanism of the constituents and influent factors (5).
It was learned that she had attempted suicide by verapamil overdose before the cardiac arrest.