vinblastine


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Related to vinblastine: vincristine

vin·blas·tine

 (vĭn-blăs′tēn′)
n.
An alkaloid, C46H58N4O9, originally obtained from the Madagascar periwinkle and used in the form of its sulfate as an antineoplastic drug.

[Short for vincaleukoblastine : New Latin Vinca, periwinkle genus; see vinca + English leukoblast, a developing leukocyte (leuko- + -blast) + -ine.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

vinblastine

(vɪnˈblæstiːn)
n
(Pharmacology) a cytotoxic drug used in the treatment of lymphomas, derived as an alkaloid from the tropical shrub Madagascar periwinkle (Vinca rosea)
[C20: shortened from vincaleukoblastine, from vinca + leukoblast, from leukocyte + -blast + -ine2]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.vinblastine - periwinkle plant derivative used as an antineoplastic drug (trade name Velban) that disrupts cell division
periwinkle plant derivative - an antineoplastic drug used to treat some forms of cancer
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

vinblastine

n vinblastina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
This plant naturally makes vinblastine through a series of complex chemical reactions.
Salvage chemotherapy regimens consist of ifosfamide (Ifex[R]), cisplatin, and either etoposide or vinblastine (Velban[R]).
In fact, not only should CAST preserve the sensitivity of the cancer cells towards chemotherapeutic agents, such as vincristine, doxorubicin, vinblastine and etoposide (among others), but it is expected to even restore it where lost, such as in chemotherapy refractory tumors.
She had been given a lumbar injection of vinblastine, a drug in the same family as vincristine, by mistake.
Retinoid gets, cryotherapy (freezing the lesions with liquid nitrogen), interferon, vinblastine, daunorubicin, or doxorubicin are some options that your doctor or dentist may consider.
Tannehill[12] conducted a trial in which amifostine was administered before 2 cycles of induction chemotherapy (cisplatin and vinblastine) and thoracic radiation.
Aside from mitoxantrone and glucocorticoids, current trials are focusing on ketoconazole, estramustine phosphate, vinblastine, and suramin (Vogelzang et al., 1998; Waselenko & Dawson, 1997).
Testing the in-vitro action of grapefruit juice on the absorption of a variety of drugs that included cyclosporine, vinblastine, losartan, digoxin, and fexofenadine, the investigators discovered that the juice reduced absorption of all.
seedlings treated with the plant alkaloid vinblastine. They speculated that this lipid material may be present because of either a direct effect of vinblastine on lipid metabolism or to the effect of vinblastine binding to the membrane, which leads to an increased production of membrane lipids.
Vinblastine and vincristine cause double vision, loss of bladder control, impotence, and paralysis of the bowel wall.
- The European Commission extended the current marketing authorization of Adcetris (brentuximab vedotin) to include treatment of adult patients with previously untreated CD30+ Stage IV Hodgkin lymphoma in combination with AVD (Adriamycin, vinblastine and dacarbazine), Takeda Pharmaceutical company Ltd.