vinca alkaloid


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vinca alkaloid

n
(Pharmacology) med any of a group of alkaloids obtained from the periwinkle Vinca rosea, such as vinblastine and vincristine, that interfere with cell division and are used in the treatment of cancer
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Phase I and pharmacokinecti study of the new vinca alkaloid vinflunine administered as a 10-min infusion every 3 weeks in patients with advenced solid tumors.
(3) Additionally, the use of a vinca alkaloid in conjunction with a steroid is associated with better outcomes than either of these agents alone.
In this study we assess the efficacy of vincristine sulphate, a vinca alkaloid used in cancer therapy, in inducing and sustaining remission in SRNS.
The chemotherapy drug is a very potent vinca alkaloid. Endocyte has completed two multi-center single arm studies of EC145 in patients with advanced ovarian cancer and advanced non-small cell lung cancer.
In 1976, Potier's team discovered that the Tubulin test proved a semi-synthesis of one vinca alkaloid compound to be active, showing promise as an anticancer drug.
Conophylline (27): Conophylline (27) is a vinca alkaloid from T.
Patients who fail to improve on this regimen should be given a course of either a vinca alkaloid or etoposide.
Vintafolide is an investigational, injectable SMDC featuring folate (vitamin B9) linked to a potent vinca alkaloid cytotoxic agent, desacetylvinblastine hydrazide (DAVLBH).
Vintafolide is an investigational, proprietary, injectable SMDC consisting of folate (vitamin B9) linked to a potent vinca alkaloid cytotoxic agent, desacetylvinblastine hydrazide (DAVLBH).
Vintafolide is an investigational proprietary, injectable, SMDC consisting of folate (vitamin B9) linked to a potent vinca alkaloid chemotherapy agent, desacetylvinblastine hydrazide (DAVLBH).
Vintafolide is a conjugate of the vitamin folate and a super-potent vinca alkaloid. Etarfolatide is a folate-targeted molecular imaging agent that is being developed as a non-invasive method to identify tumours that over-express folate receptors.