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Related to vincristine: cyclophosphamide, methotrexate, prednisone


An alkaloid, C46H56N4O10, originally obtained from the Madagascar periwinkle and used in its sulfate form to treat acute leukemia and a variety of other neoplasms.

[New Latin Vinca, periwinkle genus; see vinca + Latin crista, crest; see crest + -ine.]


(Pharmacology) a cytotoxic drug used in the treatment of leukaemia, derived as an alkaloid from the tropical shrub Madagascar periwinkle (Vinca rosea)
[C20: from New Latin vinca + Latin crista crest + -ine2]


(vɪnˈkrɪs tin)

an alkaloid, C46H56N4O10, derived from the periwinkle, Vinca rosea, used in treating certain cancers.
[1960–65; < New Latin Vin(ca) a periwinkle genus + Latin crist(a) crest + -ine2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.vincristine - periwinkle plant derivative used as an antineoplastic drug (trade name Oncovin); used to treat cancer of the lymphatic system
periwinkle plant derivative - an antineoplastic drug used to treat some forms of cancer


n vincristina
References in periodicals archive ?
Vincristine sulfate, as a single agent given IV once weekly, 4-8 doses is most common treatment protocol for TVT.
Literature Review Author Chemotherapy Radiation Surgery Regimen for PNET for PNET for PNET Barasch [1] none 41Gy none Brustle [2] type not 50Gy none specified none 79Gy none type not 30Gy none specified Chan [4] vincristine, none complete lomustine, and resection prednisone Chan [5] none 36Gy with none 54 Gy boost none 54Gy none Chen [6] not specified none subtotal resection Dorfmuller [7] type not dose not none specified specified Hader [8] none none complete resection not specified none subtotal resection procarbazine, none subtotal CCNU, vincristine resection (PCV) pcv none subtotal resection Mackenzie [11] none none subtotal resection Sedney bevasizumab and 12.
The IVADo regimen-a pilot study with ifosfamide, vincristine, actinomycin D, and doxorubicin in children with metastatic soft tissue sarcoma: a pilot study of behalf of the European pediatric Soft tissue sarcoma Study Group.
Preoperative chemotherapy with vincristine and actinomycin D brought about gross reduction in the size of the tumor (table2).
The treatment started with rituximab (500 mg/day), cyclophosphamide (1125 mg/day), adriablastine (80 mg/day), vincristine (2 mg/day), and prednisolone (80 mg/day).
bleomycin, vincristine, vinblastine, and an anthracycline (doxorubicin)--have activity in the treatment of KS, but in the developed world, liposomal doxorubicin and a taxane group constitute the backbone of current systemic chemotherapy against KS.
Primary Objective: To compare overall survival (OS) among subjects 60 years of age and older with newly diagnosed ALL who receive Marqibo versus standard vincristine as a component of multi-agent induction, intensification, and maintenance chemotherapy.
Another common cause of acute flaccid paralysis in children with ALL, is the vincristine induced peripheral neuropathy.