Twelve week regimen of once daily daclatasvir plus sofosbuvir has showen good results in patients with HCV genotype 3 with sustained virological
response of 91%.7 ALLY 3 phase III study also showed good virological
response in genotype 3 treatment naive and treatment experienced patients.8 Treatment naive patients had 96% SVR rates as compared to treatment experienced patients (86%) with higher SVR rates in patients without cirrhosis.
The company has released the first presentation of data from the Phase 3 DRIVE-SHIFT trial assessing a switch of medication to Delstrigo, a once-daily fixed-dose combination tablet of doravirine (100mg), lamivudine (3TC, 300mg) and tenofovir disoproxil fumarate (TDF, 300mg), in adults with HIV-1 infection who showcased virological
suppression for around six months on a stable antiretroviral treatment regimen.
Merck announced the first presentation of data from the Phase 3 DRIVE-SHIFT trial evaluating a switch of medication to DELSTRIGO, a once-daily fixed-dose combination tablet of doravirine (100 mg), lamivudine (3TC, 300 mg) and tenofovir disoproxil fumarate (TDF, 300 mg), in adults with HIV-1 infection who demonstrated virological
suppression for at least six months on a stable antiretroviral treatment regimen.
The present study investigated the responses of CHB patients to long-term oral antiviral therapy in terms of biochemical alanine aminotransferase (ALT), aspartate transaminase (AST), virological
(HBV DNA levels), serological (HBeAg, antiHBe, HBsAg, and antiHBs), and histopathological (histological activity and fibrosis scores based on the modified Knodell system).
Urine samples were collected at the end of therapy, after 12 weeks sustained virological
response, and one year post-treatment.
Laboratory of the State Sanitary and Epidemiological Surveillance Center conducted 11 researches on influenza pathogens circulating in Bishkek.
Officials said yesterday: "We are hostages to virological
The committee was told that "we are hostages to virological
fortune" as there is little scope for changing the vaccine once a decision has been made about the make-up of the flu jab for the next season - which occurs months ahead of time.
In order to detect hematological and blood chemistry changes during the development of PDD and a possible correlation with clinical signs and the virological
status, 6 African grey parrots (Psittacus erithacus) were experimentally infected with parrot bornavirus 4 (PaBV-4) by subcutaneous route.
The efficacy of these oral agents used with Ribavirin or in combination with one another yields a sustained virological
response at 12 weeks of greater than 90% among patients who are treatment naive .
Since HIV drug options are limited in our country and there are not enough studies that compare drug regimens in Turkish patients, we aimed to compare immunological and virological
responses to three different anti-retroviral regimens by using NNRTI, PI or INI in combination with NRTI.