von Willebrand's disease

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Related to von Willebrand's disease: hemophilia, Von Willebrand factor, DDAVP

von Wil·le·brand's disease

 (vŏn wĭl′ə-brăndz′, fôn vĭl′ə-bränts′)
A genetic disorder characterized by a tendency to hemorrhage, caused by a clotting factor that affects platelet adhesion.

[After Erik Adolf von Willebrand, (1870-1949), Finnish physician.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Von Willebrand's disease - a form of hemophilia discovered by Erik von Willebrandvon Willebrand's disease - a form of hemophilia discovered by Erik von Willebrand; a genetic disorder that is inherited as an autosomal recessive trait; characterized by a deficiency of the coagulation factor and by mucosal bleeding
bleeder's disease, haemophilia, hemophilia - congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.

Von Willebrand's disease

n. Von Willebrand, enfermedad de, desorden hereditario de la sangre caracterizado por episodios hemorrágicos gen. en las membranas mucosas.
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References in periodicals archive ?
Dini, "Epidemiological investigations of the prevalence of von Willebrand's disease," Blood, vol.
Its deficiency is responsible for von Willebrand's disease and can lead to oncogenesis [2, 3].
Von Willebrand's Disease. N Engl J Med 2017;376(7):701-702.
Powell, "Immunologic differentiation of classic hemophilia (factor VIII deficiency) and von Willebrand's disease, with observations on combined deficiencies of antihemophilic factor and proaccelerin (factor V) and on an acquired circulating anticoagulant against antihemophilic factor," The Journal of Clinical Investigation, vol.
Mannucci, "Von Willebrand's disease in the year 2003: towards the complete identification of gene defects for correct diagnosis and treatment," Haematologica, vol.
Mazurier, "Acquired type II von Willebrand's disease: Demonstration of a complexed inhibitor of the von Willebrand factorplatelet interaction and response to treatment," British Journal of Haematology, vol.
The patient was further investigated after delivery and the diagnosis of von Willebrand's disease type I was confirmed.
Use of different assays can influence the diagnosis of von Willebrand's disease, dependent on differing sensitivity to sample preparation and differential recognition of high molecular weight VWF forms.
The role of the platelet function analyser (PFA-100) in the characterization of patients with von Willebrand's disease and its relationships with von Willebrand factor and the ABO blood group.