Water-immiscible liquids (oils) and low melting point water-insoluble solids (waxes, resins, etc.) can be emulsified (one liquid suspended in another) to allow incorporation into a water-based formulation.
The hot water-insoluble gel (HWIG) determination was carried out by stirring 1 g of gum in 100 mL of distilled water for 30 minutes and heating the mixture in a water bath at 95[degrees]C for 1 hour; the mixture was allowed to stand at room temperature for 4 hours.
However, clinical development of this anticancer drug has been stopped because of the inability to develop an intravenous formulation of this water-insoluble, highly hydrophobic active pharmaceutical ingredient.
It is comprised of a water-insoluble nonwoven substrate with a non-uniform cross section that has a gradient of fiber density; a detergent composition solidified on the substrate in at least one zone; and a fabric conditioning composition comprised of a quaternary ammonium cationic surfactant and an additive mixture of C5-C22 alkyl triglycerides and fatty acids, which is also solidified on the substrate.