While at Cambridge, she used X-ray crystallography
to determine the structures of organic molecules, which helped her understand how living organisms functioned.
He hoped that this workshop would contribute towards enhanced knowledge understanding of use of X-Ray Crystallography
in Structural Biology.
- Sydney, Australia-based biopharmaceutical company NeuClone has released positive preclinical results of its biosimilar to Johnson and Johnson's Stelara, including 3-dimensional structure confirmation through X-ray crystallography
analysis, the company said.
is the technique which led to the discovery of the double helix structure of DNA.
Historians of science have written numerous papers and monographs on X-ray crystallography
. The Oxford University Press catalog offers several selections.
"First, the images gleaned by the X-ray crystallography
enabled us to directly re-engineer the modified TCRs to significantly reduce their contact with healthy tissue, which is proof of concept for a safer, more effective design for a next generation of cancer drugs.
One example of how X-ray crystallography
is employed in drug discovery is highlighted in a research project currently underway at the University of Adelaide.
Hodgkin's X-ray crystallography
unit at Oxford did the painstaking work, announced in 1955, to detect the structure of vitamin B-12.
The authors of the study, published in PLOS Pathogens, were able to discover the switch from one conformation to the other by working out the 3D structure of the endolysins using X-ray crystallography
and small angle X-ray scattering.
While X-ray crystallography
reveals structural changes, it does not provide details of how the electronic configurations evolve over time, where the Purdue team's work came in.
- which enables scientists to examine the make-up of molecules in graphic detail - is increasingly vital for research, especially in key fields such as the development of new drugs and the university is now ahead of the field.
She also took up a special course in crystallography and conducted research in x-ray crystallography
. She spent most of her working life as official fellow and tutor in Natural Science at Somerville where she taught chemistry for the women's colleges.