xanthine


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xan·thine

 (zăn′thēn′, -thĭn)
n.
1. A yellowish-white, crystalline purine base, C5H4N4O2, that is a precursor of uric acid and is found in blood, urine, muscle tissue, and certain plants.
2. Any of several derivatives of this compound.

xanthine

(ˈzænθiːn; -θaɪn)
n
1. (Elements & Compounds) a crystalline compound related in structure to uric acid and found in urine, blood, certain plants, and certain animal tissues. Formula: C5H4N4O2
2. (Elements & Compounds) any substituted derivative of xanthine, esp one of the three pharmacologically active methylated xanthines, caffeine, theophylline, or theobromine, which act as stimulants and diuretics

xan•thine

(ˈzæn θin, -θɪn)

n.
1. a crystalline, nitrogenous compound, C5H4N4O2, related to uric acid, occurring in urine, blood, and certain animal and vegetable tissues.
2. any derivative of this compound.
[1855–60; < French; see xantho-, -ine2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.xanthine - crystalline oxidation product of the metabolism of nucleoproteins; precursor of uric acid; found in many organs and in urine
organic compound - any compound of carbon and another element or a radical
Translations
xantin
Xanthin
xanthine

xan·thine

n. xantina, grupo de substancias tales como la cafeína estimulantes del sistema nervioso central y del corazón.
References in periodicals archive ?
Uric acid levels can be decreased by using allopurinol, a xanthine oxidase inhibitor.
Also, a significant decrease in hepatic glutathione level and xanthine dehydrogenase, superoxide dismutase and catalase activities was observed, compared with control group.
This study aimed to assess relations between xanthine serum xanthine oxidoreductases, uric acid and trace elements (Mo and Fe) in sera of cholelithiasis patients.
This extract and its potent tannins appears to inhibit an enzyme involved in the synthesis of uric acid, xanthine oxidase.
Keywords: Cinchonidine, cinchonine, quinine, noscapine, lipoxygenase, xanthine oxidase.
XOR catalyzes the oxidation of hypoxanthine to xanthine and xanthine to uric acid, which are the last two steps of purine catabolism in the highest primates.
The drug's safety and efficacy were evaluated in 1,537 participants in three randomized, placebo-controlled studies of its use in combination with a xanthine oxidase inhibitor.
Members voted 14-0 that the data in the four pivotal phase III trials submitted to the FDA contained enough evidence of a clinically meaningful beneficial effect of lesinurad in combination with a xanthine oxidase inhibitor (XOI) in the treatment of hyperuricemia associated with gout.
Reactive oxygen species (ROS), xanthine oxidase (XO), acetylcholine esterase (AChE) inhibition, lipid peroxidation by thiobarbituric acid (TBA) and ferric thiocyanate (FTC) methods, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays were carried out on the essential oil and the major component.
The product contains zero calories nor sugar, deriving its natural effect from plant-based xanthine sources of caffeine, guarana and cacao.
Xanthine Oxidoreductase (XOR) is a rate-limiting enzyme of the purine degradation pathway, oxidizing hypoxanthine into xanthine and xanthine into uric acid.
Allopurinol is an inhibitor of xanthine oxidase enzyme, which catalyzes formation of uric acid from xanthine.