4) In our patient, the history of subjective xerophthalmia
, subjective xerostomia, and positive anti-SS-A (Ro) and anti-SS-B(La) along with the results of the 5-minute Schirmer's test together supported the clinical diagnosis of pSS (5).
Vitamin A deficiency is a major global micronutrient deficiency associated with: xerophthalmia
, abnormal dryness of the conjunctiva and cornea of the eye; blindness; and weakened immune systems that can lead to premature death.
Singh V and KP West Vitamin A deficiency and xerophthalmia
among school-aged children in Southeastern Asia.
Common primary onset symptoms of pSS patients comprised of xerophthalmia
(dry eyes), xerostomia (dry mouth), joint pain, parotid enlargement, rampant caries, purpuric eruptions, a reduction in circulating blood platelets, and hypokalemic periodic paralysis.
Vitamin A activity of buriti (Mauritia vinifera Mart) and its effectiveness in the treatment and prevention of xerophthalmia
These are nutritional anemia, xerophthalmia
, and endemic goiter which may represent only the tip of the iceberg.
5% (RYGB); Symptoms are rare, 61 %-69% (BPD-DS) but include dry hair, decreased immunity, xerophthalmia
Vitamin D 25%-80% Osteomalacia, fractures, depression, myalgia, bone pain Iron 17% (LSG), 30%-45% Microcytic anemia, (post malabsorptive fatigue, dyspnea procedures) on exertion, angular stomatitis, glossitis Zinc 12% (LSG); 21 %-33% Poor wound healing, (RYGB); 74%-91 % skin lesions, (BPD-DS) dermatitis, diminished taste, hair loss, altered immune function, glossitis Copper 2% (RYGB); 10%-24% Anemia, (BPD-DS) pancytopenia, fatigue, dyspnea on exertion, spastic gait, sensory ataxia, peripheral neuropathy, paresthesias Nutrient Measurement Recommended (threshold frequency for deficiency) of screening Protein Serum albumin Every 6 months (<3.
Vitamin A deficiency precipitates in malnourished children who get debilitating fever, which can lead to blindness due to xerophthalmia
The other single-most important cause of childhood blindness in India is from Vitamin A deficiency, which causes xerophthalmia
and night blindness.
At least one extrahepatic manifestation was present in 79% of patients, the most frequent being arthralgia (57%), myalgia (50%), fatigue (48%), sicca symptoms (15%; 22 patients had xerophthalmia
, 14 had xerostomia, and six had both), hypothyroidism (12%), and thrombocytopenia (10%).
Primary Sjogren's syndrome (SjS) (pSS) is a systemic autoimmune disease characterized by dryness such as xerophthalmia
and xerostomia, and even fatigue and pain.
VAD causes numerous health problems such as nyctalopia (night blindness), xerophthalmia
(abnormal dryness of the eyeballs), keratomalacia (corneal ulcer) and visual impairment (blindness in both eyes).