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Extreme dryness and thickening of the conjunctiva, often resulting from a deficiency of vitamin A.

xer′oph·thal′mic adj.


(Pathology) pathol excessive dryness of the cornea and conjunctiva, caused by a deficiency of vitamin A. Also called: xeroma
ˌxerophˈthalmic adj


(ˌzɪər ɒfˈθæl mi ə, -ɒp-)

abnormal dryness of the eye caused by a deficiency of tears.
[1650–60; xer- + ophthalmia]
xe`roph•thal′mic, adj.

xerophthalmia, xerophthalmy

a form of conjunctivitis, the result of a deficiency of vitamin A, marked by a dry and dull condition of the eyeball. Also called xeroma.
See also: Eyes
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.xerophthalmia - abnormal dryness of the conjunctiva and cornea of the eyes; may be due to a systemic deficiency of vitamin A
dryness, waterlessness, xerotes - the condition of not containing or being covered by a liquid (especially water)


n. xeroftalmia, sequedad excesiva de la conjuntiva causada por deficiencia de vitamina A.
References in periodicals archive ?
4) In our patient, the history of subjective xerophthalmia, subjective xerostomia, and positive anti-SS-A (Ro) and anti-SS-B(La) along with the results of the 5-minute Schirmer's test together supported the clinical diagnosis of pSS (5).
Vitamin A deficiency is a major global micronutrient deficiency associated with: xerophthalmia, abnormal dryness of the conjunctiva and cornea of the eye; blindness; and weakened immune systems that can lead to premature death.
Common primary onset symptoms of pSS patients comprised of xerophthalmia (dry eyes), xerostomia (dry mouth), joint pain, parotid enlargement, rampant caries, purpuric eruptions, a reduction in circulating blood platelets, and hypokalemic periodic paralysis.
These are nutritional anemia, xerophthalmia, and endemic goiter which may represent only the tip of the iceberg.
5% (RYGB); Symptoms are rare, 61 %-69% (BPD-DS) but include dry hair, decreased immunity, xerophthalmia Vitamin D 25%-80% Osteomalacia, fractures, depression, myalgia, bone pain Iron 17% (LSG), 30%-45% Microcytic anemia, (post malabsorptive fatigue, dyspnea procedures) on exertion, angular stomatitis, glossitis Zinc 12% (LSG); 21 %-33% Poor wound healing, (RYGB); 74%-91 % skin lesions, (BPD-DS) dermatitis, diminished taste, hair loss, altered immune function, glossitis Copper 2% (RYGB); 10%-24% Anemia, (BPD-DS) pancytopenia, fatigue, dyspnea on exertion, spastic gait, sensory ataxia, peripheral neuropathy, paresthesias Nutrient Measurement Recommended (threshold frequency for deficiency) of screening Protein Serum albumin Every 6 months (<3.
Vitamin A deficiency precipitates in malnourished children who get debilitating fever, which can lead to blindness due to xerophthalmia.
The other single-most important cause of childhood blindness in India is from Vitamin A deficiency, which causes xerophthalmia and night blindness.
At least one extrahepatic manifestation was present in 79% of patients, the most frequent being arthralgia (57%), myalgia (50%), fatigue (48%), sicca symptoms (15%; 22 patients had xerophthalmia, 14 had xerostomia, and six had both), hypothyroidism (12%), and thrombocytopenia (10%).
Primary Sjogren's syndrome (SjS) (pSS) is a systemic autoimmune disease characterized by dryness such as xerophthalmia and xerostomia, and even fatigue and pain.
VAD causes numerous health problems such as nyctalopia (night blindness), xerophthalmia (abnormal dryness of the eyeballs), keratomalacia (corneal ulcer) and visual impairment (blindness in both eyes).