(2) These tumors are thought to arise from either extraosseous remnants of
dental lamina or the basal cell layer of surface epithelium, which is believed to have odontogenic potential.
Ameloblastoma commonly occurs in the posterior mandible (80%) and to a lesser extent in the posterior maxilla (20%).5,6 It usually affects adults in the 4th - 5th decades of life.7 The etiology is not known.8 It may arise from rests of
dental lamina, from a developing enamel organ, from the epithelial lining of an odontogenic cyst, or from the basal cells of the oral mucosa.9
1) a weak cytoplasmic expression of [beta]-catenin is present in the
dental lamina and the oral epithelium, as well as in the mesenchyme.
This species has three ontogeny stages before it reaches its adult stage: 1) Ammocoete (subcutaneous eyes, oral opening with folded lips, without marginal papillae, gill area arranged as furrow with seven undeveloped openings, and a brown colored body), 2) Macroftalmia (developed eyes, inner mouth with fleshy lips and supra and infraoral
dental lamina, gill openings exposed to the outside and a dark silver dorsal and ventral body coloration), 3) Hypermetamorphic (semicircular mouth opening, with oral and supra-oral odontoid pieces well-developed, eyes relatively small and covered by translucent membrane, gill opening with folds on each edge, developed dorsal fins, a silver body coloration and a bluish pigmentation on the fins) (Ruiz & Marchant, 2004).
Supernumerary tooth (ST) is defined as a tooth or a structure resembling tooth which forms from
dental lamina in addition to the normal dental formula [1, 2].
In the same region, following the formation of the
dental lamina, Fgf8, Fgf9, Fgf15, and Fgf20 are expressed, while the expression of Fgf10 in the epithelium is decreased [63].
According to the present concept, cases reported in literature under the terms "odontogenic gingival epithelial hamartoma" "hamartoma of the
dental lamina" and "peripheral ameloblastic fibrodentinoma" are actually examples of peripheral odontogenic fibroma.
Various genetic factors, an exchange in the position of the forming
dental lamina along with trauma to the deciduous tooth with the permanent incisor root dilaceration, were suggested as reasons for transposition.
Their presence in odontogenic cysts and tumors has been related to their derivation from the remnants of the
dental lamina and rest of Malassez which are known to have glycogen-rich clear cells as a typical feature [3, 8].
Remnants of
dental lamina could be the basis from which BOC arises because of histologic similarities between
dental lamina and the cyst wall, which is characterized by the presence of glycogen rich clear cells that are found both in
dental lamina and in the cyst wall (4).
Odontoma is a tumor composed of osseous tissue and develops from budding of extra-odontogenic epithelial cells from
dental lamina. It may occupies a position anywhere in mandible or maxilla but mostly the alveolar process of lower jaw is involved (Singh et al., 1993).
Background and Objectives: Keratocystic odontogenic tumor (KCOT) is a fairly common oral and maxillofacial lesion that is derived from remnants of the
dental lamina. It grows rapidly, has an aggressive behavior and hence invades the adjacent tissues.