(Pharmacology) a glycoside extracted from the leaves of the woolly foxglove (Digitalis lanata) and used in the treatment of heart failure. Formula: C41H64O14
digoxin - digitalis preparation (trade name Lanoxin) used to treat congestive heart failure or cardiac arrhythmia; helps the heart beat more forcefully
WASHINGTON -- In what could prove to be the final word in the clinical controversy over the safety of prescribing digoxin in patients with atrial fibrillation, a secondary analysis of the roughly 18,000-patient ARISTOTLE trial has come down emphatically on the side of avoiding the venerable drug.
Objective: To compare the efficacy of amiodarone and digoxin for patients who underwent valve-related cardiac surgery and had atrial fibrillation in the first 72 hours post-operatively.
A review of previous research on digoxin, which is used to treat heart failure and atrial fibrillation, suggests the drug may raise the risk of premature death.
Individuals who take the drug digoxin to treat the irregular and often rapid heartbeat associated with atrial fibrillation (AFib) may be at greater risk of death than individuals who take other medications for the condition, a new study suggests.
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