The company is also preparing an NDA with plans to file in 2019 for lonafarnib in the treatment of
Hutchinson-Gilford Progeria Syndrome (HGPS or Progeria) and Progeroid Laminopathies.
Progeroid laminopathies and Progeria, also known as
Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare and rapidly fatal genetic condition of accelerated aging in children.
Hennekam, "
Hutchinson-Gilford progeria syndrome: review of the phenotype," American Journal of Medical Genetics, vol.
"Not only does Nanog have the capacity to delay aging, it has the potential in some cases to reverse it," said Andreadis, noting that the embryonic stem cell gene worked in three different models of aging: cells isolated from aged donors, cells aged in culture, and cells isolated from patients with
Hutchinson-Gilford progeria syndrome.
The findings, published June 29 in the journal Stem Cells, also show promise in counteracting premature aging disorders such as
Hutchinson-Gilford progeria syndrome.
Hutchinson-Gilford progeria syndrome, a fatal premature aging condition, results from mutations in the gene that encodes lamin A, a protein that normally supports the membrane surrounding the nucleus.
Ashanti has
Hutchinson-Gilford progeria syndrome which means she suffers from accelerated ageing.
Berns of Foxboro died Friday because of complications from
Hutchinson-Gilford progeria syndrome, commonly known as progeria.