A rare genetic disorder of childhood that is characterized by rapid onset of the physical changes typical of old age, usually resulting in death before the age of 20. Also called Hutchinson-Gilford progeria syndrome.
[pro- + Greek gēras, old age; see geriatrics + -ia.]
(Pathology) med premature old age, a rare condition occurring in children and characterized by small stature, absent or greying hair, wrinkled skin, and other signs of old age
The findings, published June 29 in the journal Stem Cells, also show promise in counteracting premature aging disorders such as Hutchinson-Gilford progeria syndrome.
Researchers have discovered a link between deactivation of SIRT1 and progeria, a condition that results in premature accelerated aging and markedly shortened life span.
About 300 mourners gathered to pay tribute to the youngster, who was just 17 when she lost her battle with the rare ageing disorder progeria this month.
COLLEGE PARK, Md., June 2, 2014 -- Children with progeria, a rare disorder that causes premature aging, die in their teens of ailments that are common in octogenarians: heart failure and stroke.
It turned out that Sam has Hutchinson-Gilford progeria syndrome, an extremely rare genetic disease that affects about one in 4 million to 8 million children.
The new genome-editing technology could be expanded for use in a broad range of gene mutation conditions such as Huntington's disease and the rare premature aging syndrome, progeria.
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